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Your Position: Home > CXADR

CXADR

CXADR Molecule Information

Name:Calcium sensing receptor
Target Synonym:Extracellular calcium-sensing receptor,hCasR,GPRC2A,Calcium Sensing Receptor,Parathyroid Ca(2+)-Sensing Receptor 1,Severe Neonatal Hyperparathyroidism,Calcium-Sensing Receptor,HYPOC1,NSHPT,PCaR1,EIG8,HHC1,CaSR,CAR,FHH,FIH,HHC,Receptors, Calcium-Sensing,Hy

Number of Launched Drugs:5
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Approved

CXADR Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
CXR-H5222	Human	Human CXADR / CAR Protein, His Tag

CXADR Molecule Synonym Name

CXADR,CAR,CAR4/6,HCAR

CXADR Molecule Background

Coxsackie virus and adenovirus receptor (CXADR) is also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human

CXADR Public Drug Information

Name	Research Code	Research Phase	Company	First Brand Name	First Approved Country	First Indication	First Approved Company	First Approved Date	Indications	Clinical Trials
Parathyroid hormone (Shire)	423562; ALX-111; SHP-634; SHP-635; NPSP-558; NPSP-795; PTH 1-84; SB-423562; PTH (1-84); rhPTH-1-84; rhPTH (1-84)	Approved	Shire	Natpar, Natpara, Preotact	EU	Hypoparathyroidism	s:33:"Shire Pharmaceuticals Ireland Ltd";	2006-04-24	Osteoporosis; Osteoporosis, Postmenopausal; Hypoparathyroidism	Details
Etelcalcetide Hydrochloride	AMG-416; KAI-4169; ONO-5163; KAI-4169-HCl	Approved	Amgen Inc	Parsabiv	United States	Hyperparathyroidism, Secondary	s:19:"Kai Pharmaceuticals";	2016-11-11	Hyperparathyroidism, Secondary; Edema, Cardiac; Renal Insufficiency, Chronic	Details
Cinacalcet Hydrochloride	AMG-073.HCl; AMG-073; KRN-1493; NPS-1493	Approved	Amgen Inc	Sensipar/Mimpara, 盖平, Mimpara, Parareg, Regpara, Sensipar	Mainland China	Hyperparathyroidism, Secondary; Hypercalcemia; Hyperparathyroidism	s:17:"Kyowa Hakko Kirin";	2004-03-08	Hyperparathyroidism, Secondary; Parathyroid Neoplasms; Hypophosphatemia; Nephrosis; Edema, Cardiac; Hypercalcemia; Kidney Diseases; Hyperparathyroidism, Primary; Renal Insufficiency, Chronic; Hyperparathyroidism; Chronic Kidney Disease-Mineral and Bone Disorder; Kidney Failure, Chronic	Details
Strontium Ranelate	FK-481; S-12911; S-12911-2	Approved	Servier	欧思美, Osseor, Protos, Protelos	Mainland China	Osteoporosis, Postmenopausal	s:24:"Les Laboratoires Servier";	2004-09-20	Osteoporosis, Postmenopausal	Details
Evocalcet	MT-4580; KHK-7580	Approved	Mitsubishi Tanabe Pharma Corp	Orkedia	Japan	Hyperparathyroidism, Secondary	s:17:"Kyowa Hakko Kirin";	2018-03-23	Hyperparathyroidism, Secondary; Parathyroid Neoplasms; Hyperparathyroidism, Primary; Hyperparathyroidism	Details

CXADR Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
LNP-1892	LNP-1892	Phase 2 Clinical	Rubin Ltd	Hyperparathyroidism	Details
AJT-240	AJT-240; SK-1403	Phase 3 Clinical	Ea Pharma	Hyperparathyroidism, Secondary; Hyperparathyroidism	Details
Encaleret sulfate	MK-5442; JTT-305; CLTX-305	Phase 2 Clinical	Japan Tobacco (Hong Kong) Ltd	Osteoporosis; Hypocalcemia; Osteoporosis, Postmenopausal	Details
DS-9194b	DS-9194b	Phase 1 Clinical	Daiichi Sankyo Co Ltd	Osteoporosis	Details