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Your Position: Home > Progranulin


Brief Information

Target Synonym:GRN
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:6
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
PGN-H52H3 Human Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified)
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Part of Bioactivity data

 Progranulin SPR

Biotinylated Human Sortilin Protein, His,Avitag (Cat. No. SON-H82E9) captured on Biotin CAP-Series S Sensor Chip can bind Human Progranulin Protein, His Tag (Cat. No. PGN-H52H3) with an affinity constant of 0.355 μM as determined in a SPR assay (Biacore 8K) (QC tested).

Progranulin MALS images

The purity of Human Progranulin Protein, His Tag (Cat. No. PGN-H52H3) is more than 90% and the molecular weight of this protein is around 75-95 kDa verified by SEC-MALS.

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
GRN Gene Therapy(Eli Lilly And Company) PR-006 Phase 2 Clinical Eli Lilly And Company Frontotemporal Dementia Details
DNL-593 DNL-593; PTV:PGRN Phase 2 Clinical Denali Therapeutics Inc Frontotemporal Dementia Details
AVB-101 AVB-101 Phase 2 Clinical AviadoBio Ltd Frontotemporal Dementia Details
AL-101 GSK-4527226; AL-101 Phase 2 Clinical Alector Inc Nerve Degeneration; Alzheimer Disease; Parkinson Disease; Frontotemporal Dementia; Amyotrophic Lateral Sclerosis Details
PBFT-02 PBFT-02 Phase 2 Clinical Passage Bio Inc Frontotemporal Dementia Details
AG-01(A&G Pharm) AG-01(A&G Pharm) Phase 1 Clinical A&G Pharmaceutical Triple Negative Breast Neoplasms; Mesothelioma; Carcinoma, Non-Small-Cell Lung Details

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