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Your Position: Home > Angiopoietin-like 4

Angiopoietin-like 4

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Cat. No. Species Product Description Structure Purity Feature
AN4-H5243 Human Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein, His Tag
AN4-H5243-structure
AN4-H5243-sds

Angiopoietin-like 4 Molecule Synonym Name

ANGPTL4,ANGPTL2,ARP4,FIAF,HFARP,NL2,PGAR,pp1158,Angiopoietin like 4

Angiopoietin-like 4 Molecule Background

Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.

Angiopoietin-like 4 References

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