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Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
EpCAM CAR-T -01 | IIT | Solid Tumor | Gastric Cancer |
Expression analysis of human EpCAM on HEK293/Human EpCAM Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human EpCAM Stable Cell Line or negative control cell using PE-labeled anti-human EpCAM antibody.
Immobilized Human EpCAM, Llama IgG2b Fc Tag (Cat. No. EPM-H5259) at 1 μg/mL (100 μL/well) can bind Anti-EpCAM Antibody, Human IgG1 with a linear range of 0.2-8 ng/mL (QC tested).
The purity of Biotinylated Rhesus macaque EpCAM / TROP1 Protein, His,Avitag (Cat. No. EPM-R82E3) is more than 90% and the molecular weight of this protein is around 28-40 kDa verified by SEC-MALS.
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
M-701 | M-701 | Phase 3 Clinical | Wuhan Yzy Biopharma Co Ltd | Ovarian Neoplasms; Solid tumours; Hydrothorax; Stomach Neoplasms; Neoplasms; Ascites; Colorectal Neoplasms; Pleural Effusion, Malignant; Carcinoma, Non-Small-Cell Lung | Details |
Oportuzumab monatox | 4D5MOCB-ETA; VB4-845; VB-4847; B-4845; VB-845 | Phase 3 Clinical | Viventia Biotech Inc, Sesen Bio Inc | Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Neoplasms, Squamous Cell; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Mouth Neoplasms | Details |
Catumaxomab | LP000 | Phase 3 Clinical | Trion Research, Neovii Biotech Gmbh | Ovarian Neoplasms; Stomach Neoplasms; Carcinoma; Neoplasms; Carcinoma, Ovarian Epithelial; Colonic Neoplasms; Urinary Bladder Neoplasms; Ascites; Breast Neoplasms | Details |
Anti-EPCAM CAR-T cell therapy (Sinobioway) | Phase 2 Clinical | Beijing Sinobioway Bioengineering Group Co Ltd | Liver Neoplasms; Stomach Neoplasms | Details | |
DuoBody-EpCAMx4-1BB | BNT314/GEN1059; GEN-1059; GEN1059; BNT314 | Phase 2 Clinical | Biontech Se, Genmab A/S | Solid tumours; Neoplasms | Details |
IMC-001(Immunofoco) | IMC001; IMC-001 | Phase 2 Clinical | Suzhou Immunofoco Biotechnology Co Ltd | Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms | Details |
BA-3182 | BA-3182 | Phase 1 Clinical | Bioatla | Solid tumours; Adenocarcinoma | Details |
AM-928 | AM-928 | Phase 1 Clinical | AcadeMab Biomedical Inc | Solid tumours; Head and Neck Neoplasms; Thyroid Carcinoma, Anaplastic; Colorectal Neoplasms | Details |
CX-2051 | CX-2051 | Phase 1 Clinical | Immunogen Inc, Cytomx Therapeutics Inc | Solid tumours; Neoplasms; Colorectal Neoplasms | Details |
A-337 | A-337 | Phase 1 Clinical | Evive Biotech Ltd | Solid tumours; Neoplasms | Details |
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