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Your Position: Home > APCS

APCS

APCS Molecule Information

Name:Serum amyloid P-component
Target Synonym:Serum amyloid P-component;9.5S alpha-1-glycoprotein;SAP;APCS;PTX2;Serum amyloid P-component(1-203)

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase ?

APCS Protein Product ListCompare or Buy

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Cat. No.	Species	Product Description	Structure	Purity	Feature
APS-H5229	Human	Human APCS / SAP / PTX2 Protein, His Tag

APCS Molecule Synonym Name

PTX2,APCS,SAMP,SAP,Pentraxin 2

APCS Molecule Background

Serum amyloid P-component (SAP) is also known as Pentraxin 2 (PTX2), APCS, which belongs to the pentaxin family. SAP contains one pentaxin domain. PTX2 is a secreted homopentamer protein which is found in serum and urine. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. SAP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. SAP may also function as a calcium-dependent lectin. SAP has certain sequence homology with C-reactive protein (CRP).

APCS References

APCS Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Miridesap	GSK-2315698; GSK-2315698A; Ro-63-8695	Phase Ⅱ	Roche, GlaxoSmithKline, Pentraxin Therapeutics	Systemic amyloidosis	Details
Dezamizumab	GSK-2398852	Phase Ⅱ	Pentraxin Therapeutics, GlaxoSmithKline	Systemic amyloidosis	Details
Miridesap/Dezamizumab	GSK-2315698/GSK-2398852	Phase Ⅱ	Pentraxin Therapeutics, GlaxoSmithKline	Systemic amyloidosis	Details
GSK-3039294	GSK-3039294	Phase Ⅰ	GlaxoSmithKline	Amyloid light chain amyloidosis (AL amyloidosis)	Details