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Your Position: Home > GAPDH


Brief Information

Name:Glyceraldehyde-3-phosphate dehydrogenase liver
Target Synonym:OCAS, P38 Component,GAPD,EC:2.6.99.-,GAPDH,HEL-S-162eP,Epididymis Secretory Sperm Binding Protein Li 162eP,EC,Aging-Associated Gene 9 Protein,G3PD,EC 2.6.99.-,EC 1.2.1,EC:,Glyceraldehyde-3-Phosphate Dehydrogenases,Oct1 Coactivator In S Phase, 38 Kd Component,Glyceraldehyde-3-Phosphate Dehydrogenase,Peptidyl-Cysteine S-Nitrosylase GAPDH
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat. No. Species Product Description Structure Purity Feature
GAH-H5145 Human Human GAPDH / G3PDH Protein, His Tag

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Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is also known as Peptidyl-cysteine S-nitrosylase GAPDH, which is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. GAPDH can participate in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Also, GAPDH can modulate the organization and assembly of the cytoskeleton. Furthermore, GAPDH is a component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Omigapil SNT-317; TCH-346; CGP-3466; CGP-3466B; CGP-3466 maleate Phase 1 Clinical Santhera Pharmaceuticals Parkinson Disease; Muscular Atrophy; Amyotrophic Lateral Sclerosis; Muscular Dystrophies Details

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