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GAPDH

GAPDH Molecule Information

Name:Glyceraldehyde-3-phosphate dehydrogenase liver
Target Synonym:GAPDH;Peptidyl-cysteine S-nitrosylase GAPDH;GAPD;OK/SW-cl.12;Glyceraldehyde-3-phosphate dehydrogenase
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
GAH-H5145 Human Human GAPDH / G3PDH Protein, His Tag
GAH-H5145-structure
GAH-H5145-sds

GAPDH Molecule Synonym Name

GAPDH,GAPD,CDABP0047,OK/SW-cl.12

GAPDH Molecule Background

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is also known as Peptidyl-cysteine S-nitrosylase GAPDH, which is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. GAPDH can participate in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Also, GAPDH can modulate the organization and assembly of the cytoskeleton. Furthermore, GAPDH is a component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.

GAPDH References

GAPDH Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Omigapil CGP-3466; SNT-317; TCH-346; CGP-3466 maleate; CGP-3466B,CGP3466,SNT317,TCH346 Phase Ⅰ Santhera Pharmaceuticals Congenital Muscular Dystrophy Details

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