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GITR Ligand

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GITR Ligand Part of Bioactivity data

GIL-H82F8-ELISA
Biotinylated Human GITR Ligand, Avitag,Fc TagBiotinylated Human GITR Ligand, Avitag,Fc Tag (Cat. No. GIL-H82F8) ELISA bioactivity

Immobilized Human GITR, Fc Tag (Cat. No. GIR-H5254) at 2 μg/mL (100 μL/well) can bind Biotinylated Human GITR Ligand, Avitag,Fc Tag (Cat. No. GIL-H82F8) with a linear range of 4-63 ng/mL (QC tested).

GIL-H5249-ELISA
Human GITR Ligand, His TagHuman GITR Ligand, His Tag (Cat. No. GIL-H5249) ELISA bioactivity

Immobilized Human GITR Ligand, His Tag (Cat. No. GIL-H5249) at 2 μg/mL (100 μL/well) can bind Human GITR, Fc Tag (Cat. No. GIR-H5254) with a linear range of 0.1-4 ng/mL (QC tested).

GITR Ligand Molecule Synonym Name

TNFSF18,AITRL,TL6,hGITRL,GITR Ligand

GITR Ligand Molecule Background

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.

GITR Ligand References

GITR Ligand Related Molecule

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