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Your Position: Home > Glutaredoxin 1

Glutaredoxin 1

Brief Information

Name:Glutaredoxin
Target Synonym:Glutaredoxin-1,Thioltransferase,GRX,GLRX,Glutaredoxin,Thioltransferase-1,TTase-1,Glutaredoxin (Thioltransferase),GRX1,Glutaredoxins
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
GLX-H5149 Human Human Glutaredoxin 1 / GLRX1 Protein, His Tag
GLX-H5149-structure
GLX-H5149-sds
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Synonym Name

GLRX,GRX,TTase-1,GLRX1,GRX1

Background

Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Dimesna NSC-716976; BNP-7787; LP-300 Phase 2 Clinical Bionumerik Drug-Related Side Effects and Adverse Reactions; Anemia; Neutropenia; Adenocarcinoma of Lung; Breast Neoplasms; Breast Diseases; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details

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