Glutaredoxin 1 Protein - ACROBiosystems

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Glutaredoxin 1

Brief Information

Name:Glutaredoxin
Target Synonym:Glutaredoxin-1,Thioltransferase,GRX,GLRX,Glutaredoxin,Thioltransferase-1,TTase-1,Glutaredoxin (Thioltransferase),GRX1,Glutaredoxins

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 3 Clinical


GLX-H5149	Human	Human Glutaredoxin 1 / GLRX1 Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

GLX-H5149

Human

Human Glutaredoxin 1 / GLRX1 Protein, His Tag

Synonym Name

GLRX,GRX,TTase-1,GLRX1,GRX1

Background

Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.

Clinical and Translational Updates

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Dimesna	BNP-7787; NSC-716976	Phase 3 Clinical	Bionumerik	Breast Neoplasms; Breast Diseases; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis	Details