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Your Position: Home > GPD1

GPD1

Synonym Name

GPD1,GPD-C,GPDH-C,GPDH

Background

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD1), a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, is also known as GPD-C or GPDH-C. The function of GPD1 is inhibited by zinc ions and sulfate. GPD1 can also interact selectively and non-covalently with nicotinamide adenine dinucleotide (NAD), a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. Mutations in GPD1 gene are a cause of Hypertriglyceridemia, transient infantile (HTGIT).

Clinical and Translational Updates

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