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Hexokinase 1

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Synonym Name

Hexokinase 1,HK1

Background

Hexokinase-1 (HK1) is also known as Brain form hexokinase, Hexokinase type I (HK I). Hexokinase-1 is a monomer which can interact with RABL2/RABL2A. HK1 binds preferentially to GTP-bound RABL2 By similarity.HK1 interacts with VDAC1 and the HK1-VDAC1 complex interacts with ATF2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.

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