Biotinylated Monoclonal Anti-IFNγ antibody, Mouse IgG1 (13E6H6) (Cat. No. IFN-BS138) captured on CM5 chip via anti-mouse antibodies surface can bind ActiveMax® Human IFN-gamma, Tag Free (Cat. No. IFG-H4211) with an affinity constant of 1.28 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Monoclonal Anti-IFNγ antibody, Mouse IgG2a (8C5F8) (Cat. No. IFN-S120) captured on CM5 chip via anti-mouse antibodies surface can bind ActiveMax® Human IFN-gamma, Tag Free (Cat. No. IFG-H4211) with an affinity constant of 0.933 nM as determined in a SPR assay (Biacore 8K) (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Cadi-05 | Cadi-05 | Approved | National Institute Of Allergy And Infectious Diseases (Niaid) | Immuvac, Leprovac, Mycidac-C | India | Carcinoma, Non-Small-Cell Lung; Leprosy | null | 1998-01-01 | Leprosy; Carcinoma, Non-Small-Cell Lung | Details |
| Emapalumab | NI-0501 | Approved | Novimmune | Gamifant | Mainland China | Lymphohistiocytosis, Hemophagocytic | Sobi Pharmaceutical (Guangzhou) Co Ltd | 2018-11-20 | Macrophage Activation Syndrome; Still's Disease, Adult-Onset; Rare Diseases; Immune System Diseases; Arthritis, Juvenile; Lupus Erythematosus, Systemic; Lymphohistiocytosis, Hemophagocytic | Details |
| Thalidomide | NSC-66847; NSC-527179; K-17; VP-02 | Approved | Celgene Corp | Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled | Japan | Leprosy, Lepromatous | Fujimoto Pharmaceutical | 1982-01-01 | Waldenstrom Macroglobulinemia; Sarcoma; Prostatic Neoplasms; Arachnoiditis; Cholangitis, Sclerosing; Gastrointestinal Hemorrhage; Osteosarcoma; Pancreatitis, Chronic; Retinoblastoma; Sarcoma, Ewing; Lymphoma, Mantle-Cell; Prostatitis; Colitis, Ulcerative; Colorectal Neoplasms; Neuroectodermal Tumors, Primitive; Erythema Nodosum; Leprosy, Lepromatous; Endometrial Neoplasms; Appendiceal Neoplasms; Pelvic Pain; Angiodysplasia; Glioma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular; Amyotrophic Lateral Sclerosis; Vascular Malformations; Crohn Disease; Precancerous Conditions; Mycobacterium avium-intracellulare Infection; Idiopathic Pulmonary Fibrosis; Leukemia; Lymphoma, B-Cell, Marginal Zone; Lymphoma, B-Cell; Liver Neoplasms; Cough; Telangiectasia, Hereditary Hemorrhagic; Mycobacterium Infections; Rhabdomyosarcoma; Arteriovenous Malformations; Inflammatory Bowel Diseases; Stomatitis, Aphthous; Gastric Antral Vascular Ectasia; Spondylitis, Ankylosing; Myelodysplastic Syndromes; HIV Infections; Coronavirus Dise | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| OCH-NCNP1 | OCH-NCNP1 | Phase 2 Clinical | Keio University | Multiple Sclerosis; Crohn Disease | Details |
| SP-002 | SP-002; ASN-002; TG-1042 | Details | |||
| PP-001 | PP-001; KIO-101 | Phase 2 Clinical | 4sc Ag | Xerophthalmia | Details |
| AMG-811 | AMG-811 | Amgen Inc | Details | ||
| AS-1409 | AS-1409 | Emd Lexigen, Antisoma | Details | ||
| Recombinant human interferon gamma adenovirus injection | Phase 1 Clinical | Guangzhou Dabo Biological Products Co Ltd | Liver Neoplasms; Nasopharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant | Details | |
| Vidofludimus | 4SC-101; SC-12267 | Phase 2 Clinical | 4sc Ag | Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative | Details |
| Tadekinig alfa (AB2 Bio) | Phase 3 Clinical | Ab2 Bio | Macrophage Activation Syndrome; Lymphohistiocytosis, Hemophagocytic | Details | |
| PDS-0101 | PDS-0101B; PDS-0101C; PDS-0101; PDS-0101A; PDS-101 | Phase 2 Clinical | Pds Biotechnology Corporation, Merck Serono | Head and Neck Neoplasms; Papillomavirus Infections; Oropharyngeal Neoplasms | Details |
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