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Your Position: Home > IL-21 R

IL-21 R

Brief Information

Name:Interleukin 21 Receptor
Target Synonym:UNQ3121/PRO10273,Interleukin-21 receptor,IL21R,IL-21R,Interleukin 21 Receptor,Novel Interleukin Receptor,IL-21 Receptor,NILR,CD360 Antigen,CD360,IMD56,Receptors, Interleukin-21
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Phase 1 Clinical

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Cat. No. Species Product Description Structure Purity Feature
ILR-M82E3 Mouse Biotinylated Mouse IL-21 R Protein, His,Avitag™
ILR-M82E3-structure
ILR-M82E3-sds
ILR-C5259 Cynomolgus Cynomolgus IL-21 R Protein, Fc Tag (MALS verified)
ILR-C5259-structure
ILR-C5259-sds
ILR-H5226 Human Human IL-21 R Protein, His Tag (MALS verified)
ILR-H5226-structure
ILR-H5226-sds
ILR-H5257 Human Human IL-21 R Protein, Fc Tag (MALS verified)
ILR-H5257-structure
ILR-H5257-sds
ACRO Quality

Part of Bioactivity data

ILR-H5257-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human IL-21, Tag Free (Cat. No. IL1-H5213) immobilized on CM5 Chip can bind Human IL-21 R, Fc Tag (Cat. No. ILR-H5257) with an affinity constant of 0.412 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
ILR-C5259-ELISA
IL-21 R ELISA

Immobilized Cynomolgus IL-21, His Tag (Cat. No. IL1-C52H9) at 5 μg/mL (100 μL/well) can bind Cynomolgus IL-21 R, Fc Tag (Cat. No. ILR-C5259) with a linear range of 1-20 ng/mL (QC tested).

Protocol

Synonym Name

IL21R,CD360,NILR

Background

Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

Clinical and Translational Updates

Related Molecule

IL-21

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Latikafusp AMG-256 Phase 1 Clinical Amgen Inc Solid tumours; Neoplasms Details
JS-014 Exenokine-21; JS-014; AWT-008 Phase 1 Clinical Anwita Biosciences Inc Solid tumours; Neoplasms; Lymphoma Details

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