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IL-21 R

Brief Information

Name:Interleukin 21 Receptor
Target Synonym:UNQ3121/PRO10273,Interleukin-21 receptor,IL21R,IL-21R,Interleukin 21 Receptor,Novel Interleukin Receptor,IL-21 Receptor,NILR,CD360 Antigen,CD360,IMD56,Receptors, Interleukin-21
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 1 Clinical

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Synonym Name



Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

Clinical and Translational Updates

Related Molecule

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
JS-014 Exenokine-21; JS-014; AWT-008 Phase 1 Clinical Anwita Biosciences Inc Solid tumours; Neoplasms; Lymphoma Details
Latikafusp AMG-256 Phase 1 Clinical Amgen Inc Solid tumours Details

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