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Your Position: Home > IL-21 R

IL-21 R

Brief Information

Name:Interleukin 21 Receptor
Target Synonym:UNQ3121/PRO10273,Interleukin-21 receptor,IL21R,IL-21R,Interleukin 21 Receptor,Novel Interleukin Receptor,IL-21 Receptor,NILR,CD360 Antigen,CD360,IMD56,Receptors, Interleukin-21
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Phase 1 Clinical

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Part of Bioactivity data

ILR-H5257-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human IL-21, Tag Free (Cat. No. IL1-H5213) immobilized on CM5 Chip can bind Human IL-21 R, Fc Tag (Cat. No. ILR-H5257) with an affinity constant of 0.412 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

ILR-H5257-ELISA
Human IL-21 R, Fc TagHuman IL-21 R, Fc Tag (Cat. No. ILR-H5257) ELISA bioactivity

Immobilized Human IL-21, Tag Free (Cat. No. IL1-H5213) at 5 μg/mL (100 μL/well) can bind Human IL-21 R, Fc Tag (Cat. No. ILR-H5257) with a linear range of 0.006-0.05 μg/mL (QC tested).

Synonym Name

IL21R,CD360,NILR

Background

Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

Clinical and Translational Updates

Related Molecule

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AMG-256 AMG-256 Phase 1 Clinical Amgen Inc Solid tumours Details
JS-014 JS-014; AWT-008; Exenokine-21 Phase 1 Clinical Anwita Biosciences Inc Neoplasms Details

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