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IL-2 R beta

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IL-2 R beta Molecule Synonym Name


IL-2 R beta Molecule Background

Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - ? (CD25), ? (CD122) and ? (CD132) - non-covalently associating. The ? and ? chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the ?-chain, along with the ? subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

IL-2 R beta References

IL-2 R beta Related Molecule

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