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Your Position: Home > IL-2 R beta

IL-2 R beta

IL-2 R beta Part of Bioactivity data

CD2-H5221-Cell-based assay

Human FcRn Heterodimer Protein Cell_Base

Human IL-2 R beta, His Tag (SPR verified) (Cat. No. CD2-H5221) inhibits the IL-15-dependent proliferation of Mo7e cells. The EC50 for this effect is 0.38-0.45 µg/mL (Routinely tested).

Protocol

ILB-H5253-SPR

Human IL-2 R beta, Fc Tag (SPR verified) (Cat. No. ILB-H5253) captured on CM5 chip via anti-human IgG Fc antibody, can bind IL-2, Tag Free (Cat. No. IL2-H4113) with an affinity constant of 0.6 μM as determined in a SPR assay (Biacore T200) (QC tested).

Protocol

ILB-H5253-SPR

Human IL-2 R beta, Fc Tag (SPR verified) (Cat. No. ILB-H5253) captured on CM5 chip via anti-human IgG Fc antibody, can bind Human IL-15, Tag Free (SPR verified) (Cat. No. IL5-H4117) with an affinity constant of 9.5 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Protocol

IL-2 R beta Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
ILB-H82E3	Human	Biotinylated Human IL-2 R beta / CD122 Protein, His,Avitag™
ILB-H5253	Human	Human IL-2 R beta / CD122 Protein, Fc Tag (SPR verified)
CD2-H5221	Human	Human IL-2 R beta / CD122 Protein, His Tag (SPR verified)

IL-2 R beta Molecule Synonym Name

IL2RB,RP5-1170K4.6,CD122,P70-75

IL-2 R beta Molecule Background

Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - ? (CD25), ? (CD122) and ? (CD132) - non-covalently associating. The ? and ? chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the ?-chain, along with the ? subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.