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Your Position: Home > IL-33

IL-33

IL-33 Product List

Cat. No. Species Product Description Structure Purity Feature
IL3-H4112 Human Human IL-33 Protein, Tag Free
IL3-H4112-structure
IL3-H4112-sds
IL3-H4112-elisa_1

IL-33 Molecule Synonym Name

IL33,DV27,C9ORF26,IL1F11,NFHEV,DKFZp586H0523,DVS27,NFEHEV,RP11-575C20.2

IL-33 Molecule Background

Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-¦ÊB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.

IL-33 References

IL-33 Related Molecule

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