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Your Position: Home > IL-4

IL-4

IL-4 Product List

Cat. No. Species Product Description Structure Purity Feature
IL4-H82E0 Human Biotinylated Human IL-4 Protein, Avi Tag (Avitag™)
IL4-H82E0-structure
IL4-H82E0-sds
IL4-H82E0-elisa_1
IL4-H4218 Human ActiveMax® Recombinant Human IL-4
IL4-H4218-structure
IL4-H4218-sds
IL4-H4218-elisa_1

IL-4 Molecule Synonym Name

IL4,BCGF1,BSF1

IL-4 Molecule Background

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

IL-4 References

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