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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| ILT-H52H2 | Human | Human gp130 / CD130 / IL-6 R beta Protein, His Tag (MALS verified) |  |
|
|
| ILT-M5252 | Mouse | Mouse gp130 / CD130 / IL-6 R beta Protein, Fc Tag |  |
|
|
| ILT-M52H1 | Mouse | Mouse gp130 / CD130 / IL-6 R beta Protein, His Tag |  |
|
The purity of Human gp130, His Tag (Cat. No. ILT-H52H2) is more than 90% and the molecular weight of this protein is around 85-105kDa verified by SEC-MALS.
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Tocilizumab biosimilar (Bio-Thera Solutions) | BAT-1806; BIIB-800 | Approved | Bio-Thera Solutions Ltd | 施瑞立 | Mainland China | Arthritis, Rheumatoid; Arthritis, Juvenile; Cytokine Release Syndrome | Bio-Thera Solutions Ltd | 2023-01-16 | Cytokine Release Syndrome; Arthritis, Rheumatoid; Arthritis, Juvenile | Details |
| Tocilizumab biosimilar (Livzon Group) | Approved | Livzon Pharmaceutical Group Inc | 安维泰 | Mainland China | Arthritis, Rheumatoid | Livzon Mabpharm Inc | 2023-01-18 | Arthritis, Rheumatoid | Details | |
| Sarilumab | REGN-88; SAR-153191 | Approved | Sanofi, Regeneron Pharmaceuticals Inc | Kevzara | United States | Arthritis, Rheumatoid | Sanofi-Synthelabo | 2017-05-22 | Arthritis, Rheumatoid; Spondylitis, Ankylosing; Coronavirus Disease 2019 (COVID-19); Sarcoidosis; Mastocytosis, Systemic; Arthritis, Juvenile; Coronavirus Infections; Severe Acute Respiratory Syndrome; Uveitis | Details |
| Tocilizumab | MRA; HPM-1; MRA-SC; R-1569; rhPM-1; RG-1569; RO-48775533 | Approved | Chugai Pharmaceutical Co Ltd | Actemra/RoActemra, 雅美罗, Actemra, RoActemra | Japan | Arthritis, Juvenile; Arthritis, Rheumatoid; Giant Cell Arteritis; Takayasu Arteritis; Cytokine Release Syndrome; Multicentric Castleman's Disease (MCD) | null | 2005-04-11 | Rejection in heart transplantation; Polymyalgia Rheumatica; Stroke; systemic sclerosis-associated interstitial lung disease; Severe Acute Respiratory Syndrome; Coronavirus Infections; Lupus Erythematosus, Systemic; Breast Neoplasms; Coronary Disease; Takayasu Arteritis; Multicentric Castleman's Disease (MCD); Pulmonary Arterial Hypertension; Fever; Lymphoma; Graves Ophthalmopathy; Osteoarthritis; Uveitis; Pulmonary Disease, Chronic Obstructive; Uveitis, Posterior; Inflammation; Amyotrophic Lateral Sclerosis; Carcinoma, Hepatocellular; Non-ST Elevated Myocardial Infarction; Kidney Failure, Chronic; Diabetes Mellitus; Behcet Syndrome; Anemia, Sickle Cell; Myocardial Infarction; Solid tumours; Diabetes Mellitus, Type 1; Motor Neuron Disease; Cytokine Release Syndrome; HIV Infections; Polymyositis; Craniopharyngioma; Acute Chest Syndrome; Pneumonia; Depressive Disorder, Major; Giant Cell Arteritis; Uveitis, Intermediate; Hematologic Neoplasms; Dermatomyositis; Polyarticular Juvenile Idiopathic Arthritis; Schnitzl | Details |
| Satralizumab | RG-6168; SA-237 | Approved | Chugai Pharmaceutical Co Ltd | Enspryng, エンスプリング | Japan | Neuromyelitis Optica | Chugai Pharmaceutical Co Ltd | 2020-06-29 | Myasthenia Gravis; Brain Ischemia; Neuromyelitis Optica; Pulmonary Arterial Hypertension; Subarachnoid Hemorrhage; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Encephalitis | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Tocilizumab biosimilar (Fresenius kabi) | MSB-11456 | Phase 3 Clinical | Merck Serono | Arthritis, Rheumatoid | Details |
| VDJ-001 | Phase 2 Clinical | Beijing Vdjbio Co Ltd | Arthritis, Rheumatoid; Multicentric Castleman's Disease (MCD) | Details | |
| Tocilizumab biosimilar (AryoGen Pharmed) | Phase 3 Clinical | Aryogen Biopharma | Arthritis, Rheumatoid | Details | |
| Recombinant humanized anti-IL-6R antibody (Hisun Pharma) | HS-628 | Phase 3 Clinical | Zhejiang Hisun Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Arthritis | Details |
| CMAB806 | CMAB-806 | Phase 3 Clinical | Taizhou Maibo Taike Biotechnology Co Ltd | Arthritis, Rheumatoid; Arthritis | Details |
| Levilimab | BCD-089 | Phase 3 Clinical | Biocad | Coronavirus Disease 2019 (COVID-19); Arthritis, Rheumatoid | Details |
| Atexakin alfa | SON-080; r-IL-6 | Phase 2 Clinical | Merck Serono, Weizmann Institute Of Science | Peripheral Nervous System Diseases; Diabetic Neuropathies | Details |
| Olamkicept | TJ-301; FE-301; FE-999301; CR-5/18 | Phase 1 Clinical | Conaris Research Institute | Colitis, Ulcerative | Details |
| Tocilizumab biosimilar (Celltrion) | CT-P47; CT-P-47 | Phase 3 Clinical | Celltrion Inc | Arthritis, Rheumatoid | Details |
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