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MBL

MBL Molecule Information

Name:Mannose-binding protein C
Target Synonym:Collectin-1?Mannose-binding lectin?MBL?MBP1?COLEC1 ?MBL2?Mannan-binding protein?Mannose-binding protein C?MBP-C
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

MBL Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
MBL-H5220 Human Human MBL Protein
MBL-H5220-structure
MBL-H5220-sds

MBL Molecule Synonym Name

MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD

MBL Molecule Background

Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

MBL References

MBL Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Recombinant human mannose-binding lectin (NatImmune/Enzon) Phase Ⅱ NatImmune A/S, Enzon Pharmaceuticals Infectious disease Details

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