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MBL

Brief Information

Name:Mannose-binding protein C
Target Synonym:MBP1,COLEC1,Mannose-binding protein C,Mannose-binding lectin,MBP-C,MBL2,Mannose Binding Lectin 2,MBL,Mannose-Binding Lectin 2, Soluble (Opsonic Defect),Mannose-Binding Lectin (Protein C) 2, Soluble,Mannan-Binding Protein,Mannan-Binding Lectin,HSMBPC,MBL2D
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Cat. No. Species Product Description Structure Purity Feature
MBL-H5220 Human Human MBL Protein, His Tag
MBL-H5220-structure
MBL-H5220-sds

Synonym Name

MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD

Background

Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

Clinical and Translational Updates

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