Target Synonym:GPOA,Myocilin,Trabecular Meshwork-Induced Glucocorticoid Response Protein,Mutated Trabecular Meshwork-Induced Glucocorticoid Response Protein,Myocilin 55 KDa Subunit,Myocilin Trabecular Meshwork Inducible Glucocorticoid Response Protein,TIGR,Myocilin 20 k
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued
Myocilin, trabecular meshwork inducible glucocorticoid response is also known as MYOC, GLC1A, GPOA, JOAG, JOAG1, TIGR. Myocilin / MYOC contains one olfactomedin-like domain. Myocilin is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Clinical and Translational Updates