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Myocilin Molecule Information

Target Synonym:Trabecular meshwork-induced glucocorticoid response protein;MYOC;Myocilin 55 kDa subunit;TIGR;GLC1A
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

Myocilin Molecule Synonym Name


Myocilin Molecule Background

Myocilin, trabecular meshwork inducible glucocorticoid response is also known as MYOC, GLC1A, GPOA, JOAG, JOAG1, TIGR. Myocilin / MYOC contains one olfactomedin-like domain. Myocilin is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Myocilin References

Myocilin Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
ISV-205 ISV-205 Phase Ⅱ InSite Vision, Pharmacia & Upjohn Glaucoma Details

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