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NKp30

NKp30 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
NC3-H5259 Human Human NKp30 / NCR3 / CD337 Protein, Fc Tag
NC3-H5259-structure
NC3-H5259-sds
NC3-H5228 Human Human NKp30 / NCR3 / CD337 Protein
NC3-H5228-structure
NC3-H5228-sds

NKp30 Molecule Synonym Name

NCR3,CD337,NKp30,1C7,LY117,MALS

NKp30 Molecule Background

Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

NKp30 References

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