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TrkB

TrkB Product List

Cat. No. Species Product Description Structure Purity Feature
NT2-H5254 Human Human TrkB / NTRK2 Protein, Fc Tag
NT2-H5254-structure
NT2-H5254-sds
NT2-H5228 Human Human TrkB / NTRK2 Protein
NT2-H5228-structure
NT2-H5228-sds

TrkB Molecule Synonym Name

NTRK2,TRKB,GP145-TrkB

TrkB Molecule Background

Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is ¡°ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate¡±. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.

TrkB References

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