Login Register
icon_bulk_orderBulk order Acrobiosystems for English
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > PSGL-1


Brief Information

Name:P-selectin glycoprotein ligand-1
Target Synonym:P-selectin glycoprotein ligand 1,PSGL-1,SELPLG,Selectin P Ligand,Cutaneous Lymphocyte-Associated Associated Antigen,CD162 Antigen,CD162,PSGL1,CLA
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

Product ListCompare or Buy

By Product Status:
By Product Category:
By Species:
Cat. No. Species Product Description Structure Purity Feature
PS1-H82E4 Human Biotinylated Human PSGL-1 / CD162 Protein, His,Avitag™
PS1-H52H9 Human Human PSGL-1 / CD162 Protein, His Tag
ACRO Quality

Part of Bioactivity data


Human PSGL-1, His Tag (Cat. No. PS1-H52H9) immobilized on CM5 Chip can bind Human B7-H5, Fc Tag (Cat. No. B75-H5259) with an affinity constant of 0.213 μM as determined in a SPR assay (Biacore T200) (Routinely tested).

Synonym Name

PSGL1,CD162,SELPLG,Selectin P ligand


P-selectin glycoprotein ligand 1 (PSGL-1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL-1 is disulfide-linked homodimer which is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 / SELPLG  interacts with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for P-selectin/SELP binding. PSGL-1 can interact with SNX20, MSN and SYK. PSGL-1 / SELPLG mediate the activation of SYK by SELPLG.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Neihulizumab AbGn-168; AbGn-168H Phase 1 Clinical Abgenomics Graft vs Host Disease; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative Details
SelK-2 SelK-2 Phase 2 Clinical Selexys Venous Thromboembolism; Asthma; Pulmonary Disease, Chronic Obstructive Details
SSGJ-617 SSGJ-617; SSGJ617; 61X; VTX-0811 Phase 1 Clinical Shanghai Cp Guojian Pharmaceutical Co Ltd, Verseau Therapeutics Inc Solid tumours Details
ALTB-268 ALTB-268 Phase 1 Clinical Colitis, Ulcerative Details

This web search service is supported by Google Inc.

Call us
Call us
North America: +1 800-810-0816 (Toll Free)
Asia & Pacific: +86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message