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PTH1R

Brief Information

Name:Parathyroid hormone receptor
Target Synonym:EKNS,Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor,Seven Transmembrane Helix Receptor,PFE,Receptors, Parathyroid Hormone,PTH/PTHrP type I receptor,PTH1 receptor,PTH1R,PTHR,PTHR1,Parathyroid Hormone 1 Receptor,Parathyroid Hormone Recepto
Number of Launched Drugs:15
Number of Drugs in Clinical Trials:22
Lastest Research Phase:Approved

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By Product Category:
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By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
PTR-H5222 Human Human PTH1R / PTHR1 Protein, His Tag
PTR-H5222-structure
PTR-H5222-sds

Synonym Name

PTH1R,PTHR,PTHR1

Background

Parathyroid hormone/parathyroid hormone-related peptide receptor is also known as Parathyroid hormone 1 receptor (PTH1R), PTHR1, PTH/PTHrP type I receptor (PTH/PTHr receptor), which belongs to the G-protein coupled receptor 2 family. PTH1R / PTHR1 is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Teriparatide biosimilar (Biosidus) rhPTH (1-34) (Biosidus) Approved Biosidus Osteofortil Ecuador Osteoporosis Biosidus 2012-08-01 Osteoporosis Details
Teriparatide biosimilar (Zydus Cadila) rhPTH (1-34) (Zydus Cadila) Approved Zydus Cadila India Osteoporosis Zydus Cadila 2014-01-01 Osteoporosis Details
Teriparatide biosimilar (STADA Arzneimittel AG) rhPTH (1-34) (STADA Arzneimittel AG) Approved Stada Arzneimittel Ag Movymia EU Osteoporosis Stada Arzneimittel Ag 2017-01-11 Osteoporosis Details
Teriparatide biosimilar (Gedeon Richter) rhPTH (1-34) (Gedeon Richter) Approved Gedeon Richter Plc Terrosa EU Osteoporosis Gedeon Richter Plc 2017-01-04 Osteoporosis Details
Teriparatide biosimilar (Salubris) Approved Shenzhen Salubris Pharmaceuticals Co Ltd 欣复泰 Mainland China Osteoporosis, Postmenopausal Suzhou Genemen Biotech Co Ltd 2019-09-29 Osteoporosis, Postmenopausal Details
Teriparatide biosimilar (USV) Approved Usv Osteoporosis Details
Teriparatide biosimilar (Intas Pharmaceuticals) rhPTH (1-34) (Intas Pharmaceuticals) Approved Intas Biopharmaceuticals Terifrac India Osteoporosis Intas Biopharmaceuticals 2010-12-01 Osteoporosis Details
Teriparatide biosimilar (CinnaGen) rhPTH (1-34) (CinnaGen) Approved Cinnagen CinnoPar Iran Osteoporosis Cinnagen 2013-01-01 Osteoporosis Details
Teriparatide biosimilar (Pfenex) rhPTH (1-34) (Pfenex); PF-708 Approved Pfenex Qutavina, Bonsity United States Osteoporosis Alvogen 2019-10-04 Osteoporosis Details
Teriparatide biosimilar (Virchow/Sun) rhPTH (1-34) (Virchow/Sun) Approved Virchow Group, Sun Pharmaceutical Industries Ltd Bonista, Osteotide Osteoporosis Details
Teriparatide biosimilar (Theramex) Approved Theramex Ireland Ltd Livogiva EU Osteoporosis Theramex Ireland Ltd 2020-08-27 Osteoporosis Details
Recombinant Human Parathyroid Hormone (1-34), Shanghai Fosunpharma Approved Shanghai Fosun Pharmaceutical (Group) Co Ltd Details
Abaloparatide BA-058-SC; BA-058-TD; BIM-44058; BA-058; ITM-058 Approved Ipsen Tymlos Japan Osteoporosis, Postmenopausal Teijin Pharma 2017-04-28 Osteoporotic Fractures; Osteoporosis; Osteoporosis, Postmenopausal Details
Parathyroid hormone (Shire) 423562; ALX-111; SHP-634; SHP-635; NPSP-558; NPSP-795; PTH 1-84; SB-423562; PTH (1-84); rhPTH-1-84; rhPTH (1-84) Approved Shire Natpar, Natpara, Preotact EU Hypoparathyroidism Shire Pharmaceuticals Ireland Ltd 2006-04-24 Osteoporosis; Osteoporosis, Postmenopausal; Hypoparathyroidism Details
Teriparatide acetate hPTH (1-34) acet. H2O; AK-159; MN-10-T Approved Union Square Ventures Llc Parathar, Teribone Japan Hypocalcemia; Osteoporosis null 1987-03-31 Osteoporosis; Hypocalcemia Details
Teriparatide biosimilar (Amega Biotech) rhPTH (1-34) (Amega Biotech) Approved Amega Biotech Osteoporosis Details
Teriparatide MN-10T; hPTH-1-34; LY 333334 Approved Eli Lilly And Company Forteo, Forsteo, 复泰奥 Mainland China Osteoporosis, Postmenopausal; Osteoporosis Eli Lilly Nederland Bv 2002-11-26 Drug-Related Side Effects and Adverse Reactions; Osteoporotic Fractures; Osteoporosis; Bone Diseases, Metabolic; Osteoporosis, Postmenopausal; Colles' Fracture; Femoral Neck Fractures; Spinal Fractures; Back Pain; Hypoparathyroidism Details
Teriparatide biosimilar (Shanghai United Cell ) Approved Shanghai United Cell Biotechnology Co Ltd Mainland China Osteoporosis Shanghai United Cell Biotechnology Co Ltd 2017-03-22 Osteoporosis Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Teriparatide biosimilar (Stelis) SBL-001 Phase 1 Clinical Stelis Biopharma Osteoporosis Details
Teriparatide transdermal (Corium International) Phase 2 Clinical Corium International Inc Osteoporosis Details
KUR-111 I-0401; KUR-111 Phase 2 Clinical Kuros Biosciences Fractures, Bone Details
Teriparatide (Critical Pharmaceuticals) CP-046 Phase 1 Clinical University Of Nottingham, Critical Pharmaceuticals Osteoporosis Details
BMD-1221 BMD-1221 Clinical University Of Arkansas System Fractures, Bone Details
T3-sulfate (Bracco SpA) Phase 2 Clinical Bracco Hypothyroidism Details
Teriparatide biosimilar (Shanghai CAS Shenglongda Biotech) Phase 3 Clinical Shanghai Zhongke Shenglongda Biotechnology (Group) Co Ltd Osteoporosis, Postmenopausal Details
Hemoparatide hPTH-137 Phase 1 Clinical Pharis Biotec Psoriasis Details
Teriparatide biosimilar (National Institute of Dental and Craniofacial Research) rhPTH (1-34) (National Institute of Dental and Craniofacial Research) Phase 3 Clinical National Institute Of Dental And Craniofacial Research DiGeorge Syndrome; Hypothyroidism Details
Teriparatide biosimilar (Shanghai Fudan-Zhangjiang Bio-Pharmaceutical) Phase 1 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Osteoporosis Details
Recombinant human parathyroid hormone (Shenzhen Salubris Pharmaceuticals) SAL-001; G56-W1; rhPTH(1-34) Phase 2 Clinical Shenzhen Salubris Pharmaceuticals Co Ltd Osteoporosis; Osteoporosis, Postmenopausal Details
Teriparatide biosimilar (Dongguan Baolijian Bioengineer) Phase 3 Clinical Dongguan Baolijian Bioengineering Research And Development Co Ltd Osteoporosis; Osteoporosis, Postmenopausal Details
KUR-113 KUR-113; I-040202; Fibrin-PTH Phase 2 Clinical Kuros Biosciences Spinal Diseases; Intervertebral Disc Degeneration; Fractures, Bone Details
Parathyroid hormone 1-84 (Kerun Biopharmaceutical) Phase 3 Clinical Chongqing Kerun Biologic Pharmaceutical Development Co Ltd Osteoporosis, Postmenopausal; Hypoparathyroidism Details
Recombinant Human Parathyroid Hormone (1-34)(Shanghai Celgen Biopharmaceuticals) Phase 2 Clinical Shanghai Celgen Bio-Pharmaceutical Co Ltd Osteoporosis Details
Recombinant Teriparatide(Beijing Bokangjian Gene) Phase 1 Clinical Beijing Bokangjian Gene Technology Co Ltd Osteoporosis, Postmenopausal Details
TransCon PTH ACP-014 Phase 3 Clinical Ascendis Pharma Parathyroid Diseases; Hypoparathyroidism Details
MT-1013 MT-1013 Phase 1 Clinical Shaanxi Micot Technology Co Ltd Hyperparathyroidism, Secondary Details

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