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PTH1R

PTH1R Molecule Information

Name:Parathyroid hormone receptor
Target Synonym:EKNS,Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor,Seven Transmembrane Helix Receptor,PFE,Receptors, Parathyroid Hormone,PTH/PTHrP type I receptor,PTH1 receptor,PTH1R,PTHR,PTHR1,Parathyroid Hormone 1 Receptor,Parathyroid Hormone Recepto
Number of Launched Drugs:15
Number of Drugs in Clinical Trials:22
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
PTR-H5222 Human Human PTH1R / PTHR1 Protein, His Tag
PTR-H5222-structure
PTR-H5222-sds

PTH1R Molecule Synonym Name

PTH1R,PTHR,PTHR1

PTH1R Molecule Background

Parathyroid hormone/parathyroid hormone-related peptide receptor is also known as Parathyroid hormone 1 receptor (PTH1R), PTHR1, PTH/PTHrP type I receptor (PTH/PTHr receptor), which belongs to the G-protein coupled receptor 2 family. PTH1R / PTHR1 is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

PTH1R References

PTH1R Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Teriparatide biosimilar (Biosidus) rhPTH (1-34) (Biosidus) Approved Biosidus Osteofortil Ecuador Osteoporosis s:8:"Biosidus"; 2012-08-01 Osteoporosis Details
Teriparatide biosimilar (Zydus Cadila) rhPTH (1-34) (Zydus Cadila) Approved Zydus Cadila India Osteoporosis s:12:"Zydus Cadila"; 2014-01-01 Osteoporosis Details
Teriparatide biosimilar (STADA Arzneimittel AG) rhPTH (1-34) (STADA Arzneimittel AG) Approved Stada Arzneimittel Ag Movymia EU Osteoporosis s:21:"Stada Arzneimittel Ag"; 2017-01-11 Osteoporosis Details
Teriparatide biosimilar (Gedeon Richter) rhPTH (1-34) (Gedeon Richter) Approved Gedeon Richter Plc Terrosa EU Osteoporosis s:18:"Gedeon Richter Plc"; 2017-01-04 Osteoporosis Details
Teriparatide biosimilar (Salubris) Approved Shenzhen Salubris Pharmaceuticals Co Ltd 欣复泰 Mainland China Osteoporosis, Postmenopausal s:29:"Suzhou Genemen Biotech Co Ltd"; 2019-09-29 Osteoporosis, Postmenopausal Details
Recombinant Teriparatide(Shanghai United Cell ) Approved Shanghai United Cell Biotechnology Co Ltd Mainland China Osteoporosis s:41:"Shanghai United Cell Biotechnology Co Ltd"; 2017-03-22 Osteoporosis Details
Teriparatide acetate AK-159; MN-10-T; hPTH (1-34) acet. H2O Approved Union Square Ventures Llc Parathar, Teribone Japan Osteoporosis; Hypocalcemia s:4:"null"; 1987-03-31 Osteoporosis; Hypocalcemia Details
Abaloparatide BA-058; ITM-058; BA-058-SC; BA-058-TD; BIM-44058 Approved Ipsen Tymlos United States Osteoporosis, Postmenopausal s:17:"Radius Health Inc"; 2017-04-28 Osteoporotic Fractures; Osteoporosis; Osteoporosis, Postmenopausal Details
Teriparatide biosimilar (USV) Approved Usv N; Osteoporosis Details
Teriparatide biosimilar (Virchow/Sun) rhPTH (1-34) (Virchow/Sun) Approved Virchow Group, Sun Pharmaceutical Bonista, Osteotide N; Osteoporosis Details
Teriparatide biosimilar (Intas Pharmaceuticals) rhPTH (1-34) (Intas Pharmaceuticals) Approved Intas Biopharmaceuticals Terifrac India Osteoporosis s:24:"Intas Biopharmaceuticals"; 2010-12-01 Osteoporosis Details
Teriparatide (Amega Biotech) rhPTH (1-34) (Amega Biotech) Approved Amega Biotech N; Osteoporosis Details
Teriparatide biosimilar (CinnaGen) rhPTH (1-34) (CinnaGen) Approved Cinnagen CinnoPar Iran Osteoporosis s:8:"Cinnagen"; 2013-01-01 Osteoporosis Details
Teriparatide biosimilar (Theramex) Approved Theramex Ireland Ltd Livogiva EU Osteoporosis s:20:"Theramex Ireland Ltd"; 2020-08-27 Osteoporosis Details
Teriparatide biosimilar (Pfenex) rhPTH (1-34) (Pfenex); PF-708 Approved Pfenex Qutavina, Bonsity United States Osteoporosis s:7:"Alvogen"; 2019-10-04 Osteoporosis Details
Parathyroid hormone (Shire) 423562; ALX-111; SHP-634; SHP-635; NPSP-558; NPSP-795; PTH 1-84; SB-423562; PTH (1-84); rhPTH-1-84; rhPTH (1-84) Approved Shire Natpar, Natpara, Preotact EU Hypoparathyroidism s:33:"Shire Pharmaceuticals Ireland Ltd"; 2006-04-24 Osteoporosis; Osteoporosis, Postmenopausal; Hypoparathyroidism Details
Teriparatide LY 333334; MN-10T; hPTH-1-34 Approved Eli Lilly And Company 复泰奥, Forteo, Forsteo Mainland China Osteoporosis; Osteoporosis, Postmenopausal s:22:"Eli Lilly Nederland Bv"; 2002-11-26 Osteoporotic Fractures; Drug-Related Side Effects and Adverse Reactions; Osteoporosis; Bone Diseases, Metabolic; Osteoporosis, Postmenopausal; Colles' Fracture; Femoral Neck Fractures; Back Pain; Spinal Fractures; Hypoparathyroidism Details

PTH1R Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Teriparatide biosimilar (Stelis) SBL-001 Phase 1 Clinical Stelis Biopharma Osteoporosis Details
KUR-113 KUR-113; I-040202; Fibrin-PTH Phase 2 Clinical Kuros Biosciences Intervertebral Disc Degeneration; Fractures, Bone Details
Teriparatide transdermal (Corium International) Phase 2 Clinical Corium International Inc Osteoporosis Details
AJT-240 AJT-240; SK-1403 Phase 3 Clinical Ea Pharma Hyperparathyroidism, Secondary; Hyperparathyroidism Details
KUR-111 I-0401; KUR-111 Phase 2 Clinical Kuros Biosciences Fractures, Bone Details
Teriparatide (Critical Pharmaceuticals) CP-046 Phase 1 Clinical University Of Nottingham, Critical Pharmaceuticals Osteoporosis Details
BMD-1221 BMD-1221 Clinical University Of Arkansas System Fractures, Bone Details
Recombinant human parathyroid hormone 1-34 (Shanghai United Cell Biotech) rhPTH (1-34) Phase 3 Clinical Shanghai United Cell Biotechnology Co Ltd Osteoporosis Details
T3-sulfate (Bracco SpA) Phase 2 Clinical Bracco Hypothyroidism Details
Teriparatide biosimilar (Shanghai CAS Shenglongda Biotech) Phase 3 Clinical Shanghai Zhongke Shenglongda Biotechnology (Group) Co Ltd Osteoporosis, Postmenopausal Details
Recombinant Human Parathyroid Hormone (1-34), Shanghai Celgen Biopharmaceuticals Phase 2 Clinical Shanghai Celgen Bio-Pharmaceutical Co Ltd Osteoporosis Details
Hemoparatide hPTH-137 Phase 1 Clinical Pharis Biotec Psoriasis Details
Teriparatide biosimilar (National Institute of Dental and Craniofacial Research) rhPTH (1-34) (National Institute of Dental and Craniofacial Research) Phase 3 Clinical National Institute Of Dental And Craniofacial Research DiGeorge Syndrome; Hypothyroidism Details
Teriparatide biosimilar (Shanghai Fudan-Zhangjiang Bio-Pharmaceutical) Phase 1 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Osteoporosis Details
Recombinant human parathyroid hormone (Shenzhen Salubris Pharmaceuticals) SAL-001; G56-W1; rhPTH(1-34) Phase 2 Clinical Shenzhen Salubris Pharmaceuticals Co Ltd Osteoporosis; Osteoporosis, Postmenopausal Details
Teriparatide biosimilar (Dongguan Baolijian Bioengineer) Phase 3 Clinical Dongguan Baolijian Bioengineering Research And Development Co Ltd Osteoporosis; Osteoporosis, Postmenopausal Details
Parathyroid hormone 1-84 (Kerun Biopharmaceutical) Phase 3 Clinical Chongqing Kerun Biologic Pharmaceutical Development Co Ltd Osteoporosis, Postmenopausal; Hypoparathyroidism Details
TransCon PTH ACP-014 Phase 3 Clinical Ascendis Pharma Parathyroid Diseases; Hypoparathyroidism Details

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