Serpin F1 Protein - ACROBiosystems

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Serpin F1

Brief Information

Name:Pigment epithelium-derived factor
Target Synonym:Testis Tissue Sperm-Binding Protein Li 70n,SERPINF1,Serpin F1,Cell proliferation-inducing gene 35 protein,EPC-1,Serpin Family F Member 1,Proliferation-Inducing Protein 35,OI12,Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1,Alpha-2 Antiplasmin,PIG35,Serine (Or Cysteine) Proteinase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1,OI6

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical


SE1-H5221	Human	Human Serpin F1 / PEDF Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

SE1-H5221

Human

Human Serpin F1 / PEDF Protein, His Tag

Synonym Name

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

Background

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Clinical and Translational Updates

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
DVC1-0401	DVC1-0401	Phase 2 Clinical	Kyushu University, Id Pharma	Retinitis Pigmentosa	Details
BRM-421	BRM-421		Brim Biotechnology Co Ltd		Details

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Serpin F1

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