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Siglec-6

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Cat. No. Species Product Description Structure Purity Feature
SI6-H5256 Human Human Siglec-6 / CD327 Protein, Fc Tag
SI6-H5256-structure
SI6-H5256-sds

Synonym Name

SIGLEC6,CD327,CD33L,CD33L1,OBBP1,OB-BP1,CDw327

Background

Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Clinical and Translational Updates

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