SLITRK6 Protein - ACROBiosystems

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SLITRK6

Brief Information

Name:SLIT and NTRK-like protein 6
Target Synonym:SLITRK6,SLIT And NTRK Like Family Member 6,SLIT And NTRK-Like Family, Member 6,SLIT And NTRK-Like Protein 6,Slit And Trk Like Gene 6,4832410J21Rik,DFNMYP,FLJ22774

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical


SL6-H5226	Human	Human SLITRK6 Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

SL6-H5226

Human

Human SLITRK6 Protein, His Tag

Synonym Name

SLITRK6

Background

SLIT and NTRK-like protein 6 (SLITRK6) belongs to the SLITRK family. SLITRK6 contains 11 LRR (leucine-rich) repeats, two LRRCT domains and two LRRNT domains. In adult brain, SLITRK6 is highly expressed in putamen and also is expressed in adult, fetal lung and fetal liver. SLITRK6 is also expressed at high levels in some brain tumors. Overexpression of SLITRK6 inhibites neurite outgrowth in cultured neurons.

Clinical and Translational Updates

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
sirtratumab vedotin	AGS-15E; ASG-15ME; AGS15C–SGD-1006; Ha15-10ac.1vcMMAE; Ha15-10ac12vcMMAE	Phase 1 Clinical	Agensys, Seattle Genetics	Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Urogenital Neoplasms	Details