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Your Position: Home > SLITRK6

SLITRK6

Brief Information

Name:SLIT and NTRK-like protein 6
Target Synonym:SLITRK6,SLIT And NTRK Like Family Member 6,SLIT And NTRK-Like Family, Member 6,SLIT And NTRK-Like Protein 6,Slit And Trk Like Gene 6,4832410J21Rik,DFNMYP,FLJ22774
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat. No. Species Product Description Structure Purity Feature
SL6-H5255 Human Human SLITRK6 Protein, Mouse IgG2a Fc Tag (MALS verified)
SL6-H5255-structure
SL6-H5255-sds
SL6-H5255-elisa_1
SL6-H5226 Human Human SLITRK6 Protein, His Tag
SL6-H5226-structure
SL6-H5226-sds
SL6-H5226-elisa_1

Part of Bioactivity data

SL6-H5226-ELISA
Human SLITRK6, His TagHuman SLITRK6, His Tag (Cat. No. SL6-H5226) ELISA bioactivity

Immobilized Human SLITRK6, His Tag (Cat. No. SL6-H5226) at 2 μg/mL (100 μL/well) can bind Sirtratumab with a linear range of 0.001-0.5 μg/mL (Routinely tested).

SL6-H5255-MALS-HPLC
Human SLITRK6, Mouse IgG2a Fc Tag (Cat. No. ) MALS images

The purity of Human SLITRK6, Mouse IgG2a Fc Tag (Cat. No. SL6-H5255) is more than 90% and the molecular weight of this protein is around 186-227 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human SLITRK6, Mouse IgG2a Fc TagHuman SLITRK6, Mouse IgG2a Fc Tag (Cat. No. SL6-H5255) ELISA bioactivity

Immobilized Human SLITRK6, Mouse IgG2a Fc Tag (Cat. No. SL6-H5255) at 2 μg/mL (100 μL/well) can bind Sirtratumab with a linear range of 0.5-31 ng/mL (QC tested).

Synonym Name

SLITRK6

Background

SLIT and NTRK-like protein 6 (SLITRK6) belongs to the SLITRK family. SLITRK6 contains 11 LRR (leucine-rich) repeats, two LRRCT domains and two LRRNT domains. In adult brain, SLITRK6 is highly expressed in putamen and also is expressed in adult, fetal lung and fetal liver. SLITRK6 is also expressed at high levels in some brain tumors. Overexpression of SLITRK6 inhibites neurite outgrowth in cultured neurons.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
sirtratumab vedotin AGS-15E; ASG-15ME; AGS15C–SGD-1006; Ha15-10ac.1vcMMAE; Ha15-10ac12vcMMAE Phase 1 Clinical Agensys, Seattle Genetics Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Urogenital Neoplasms Details

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