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TGF-beta 1

TGF-beta 1 Part of Bioactivity data

TG1-H4212-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

ActiveMax® Human TGFB1, Tag Free (Cat. No. TG1-H4212) inhibits the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 0.390-0.476 pg/ml (Routinely tested).

ActiveMax® Human TGFB1, Tag FreeActiveMax® Human TGFB1, Tag Free (Cat. No. TG1-H4212) ELISA bioactivity

Immobilized ActiveMax® Human TGFB1, Tag Free (Cat. No. TG1-H4212) at 2 μg/mL (100 μL/well) can bind Human TGFBR2, Fc Tag (Cat. No. TG2-H5252) with a linear range of 0.3-5 ng/mL (QC tested).

Biotinylated Human TGF-Beta 1, Avitag™Biotinylated Human TGF-Beta 1, Avitag™ (Cat. No. TG1-H8217) ELISA bioactivity

Immobilized Human TGFBR2, Fc Tag (Cat. No. TG2-H5252) at 5 μg/mL (100 μL/well) can bind Biotinylated Human TGF-Beta 1, Avitag (Cat. No. TG1-H8217) with a linear range of 0.8-13 ng/mL (QC tested).

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Cat. No. Species Product Description Structure Purity Feature
TG1-H8217 Human Biotinylated Human TGF-Beta 1 / TGFB1 Protein, Avitag™
TG1-H4212 Human ActiveMax® Human TGF-Beta 1 / TGFB1 Protein, Tag Free

TGF-beta 1 Customer Reviews

TGF-beta 1 Molecule Synonym Name


TGF-beta 1 Molecule Background

Transforming growth factor beta 1 ( TGFB1) is also known as TGF-?1, CED, DPD1, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.  The TGFB1 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB1 protein is found throughout the body and plays a role in development before birth, the formation of blood vessels, the regulation of muscle tissue and body fat development, wound healing, and immune system function. TGFB1 is particularly abundant in tissues that make up the skeleton, where it helps regulate bone growth, and in the intricate lattice that forms in the spaces between cells (the extracellular matrix). Within cells, this protein is turned off (inactive) until it receives a chemical signal to become active. TGFB1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGFB1. TGFB1 has been shown to interact with TGF beta receptor 1, LTBP1, YWHAE, EIF3I  and Decorin.

TGF-beta 1 References

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