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DcR3

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Cat. No. Species Product Description Structure Purity Feature
TNB-H5255 Human Human DcR3 / TNFRSF6B Protein, Fc Tag
TNB-H5255-structure
TNB-H5255-sds
TNB-H5255-elisa_1

DcR3 Part of Bioactivity data

TNB-H5255-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human DcR3, Fc Tag (Cat. No. TNB-H5255) on AHC Biosensor, can bind Human LIGHT, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. LIT-H5256) with an affinity constant of 1.64 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

TNB-H5255-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human DcR3, Fc Tag (Cat. No. TNB-H5255) on AHC Biosensor, can bind Human LIGHT, His Tag (Cat. No. LIT-H5247) with an affinity constant of 4.94 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

DcR3 Molecule Synonym Name

TNFRSF6B,DCR3,TR6,M68

DcR3 Molecule Background

Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.

DcR3 References

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