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Brief Information

Name:Tissue factor
Target Synonym:Coagulation Factor III (Thromboplastin, Tissue Factor),Thromboplastin,Coagulation Factor III, Tissue Factor,TFA,F3,TF,CD142 Antigen,CD142,Coagulation Factor III,Tissue Factor
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Approved

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Part of Bioactivity data

CHEK-ATP115-Cell-based assay
 Transferrin FACS

Expression analysis of human Transferrin on HEK293/Human Transferrin Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Transferrin Stable Cell Line or negative control cell using PE-labeled anti-human Transferrin antibody.

 Transferrin SPR

Biotinylated Human Transferrin Protein, His,Avitag (Cat. No. TRN-H82E3) captured on Biotin CAP-Series S Sensor Chip can bind Human Transferrin R, His Tag (Cat. No. CD1-H5243) with an affinity constant of 0.527 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

 Transferrin ELISA

Immobilized Biotinylated Human Transferrin R Protein, Fc,Avitag (Cat. No. TFR-H82F3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Biotinylated Human Transferrin R Protein, Fc,Avitag (Cat. No. TRN-H52H3) with a linear range of 5-78 ng/mL (QC tested).

Synonym Name



Transferrin is also known as Serotransferrin, Beta-1 metal-binding globulin, TF, and is iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. Although iron bound to transferrin is less than 0.1% (4

Related Molecule

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Tisotumab vedotin TF-011-MMAE Approved Genmab A/S HuMax-TF, TIVDAK United States Uterine Cervical Neoplasms Seagen Inc 2021-09-20 Ovarian Neoplasms; Solid tumours; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Anpocogin AB-201 Phase 3 Clinical Dendreon Uk Ltd Coronavirus Disease 2019 (COVID-19) Details
XNW-28012 XNW-28012; XNW28012 Phase 2 Clinical Shanghai Cigna Biotech Pharmaceutical Co Ltd Solid tumours Details
MRG-004A MRG004A Phase 2 Clinical Shanghai Miracogen Inc Solid tumours Details
XB-002 XB-002; ICON-2 Phase 1 Clinical Iconic Therapeutics Inc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Urogenital Neoplasms; Esophageal Squamous Cell Carcinoma; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details

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