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VEGF R1

VEGF R1 Product List

Cat. No. Species Product Description Structure Purity Feature
VE1-H5220 Human Human VEGF R1 / Flt-1 Protein
VE1-H5220-structure
VE1-H5220-sds
VE1-H5220-elisa_1
VE1-H82E3 Human Biotinylated Human VEGF R1 / Flt-1 Protein, His Tag, Avi Tag (Avitag™)
VE1-H82E3-structure
VE1-H82E3-sds
VE1-H82E3-elisa_1
VE1-M5256 Mouse Mouse VEGF R1 / Flt-1 Protein, Mouse IgG2a Fc Tag, low endotoxin
VE1-M5256-structure
VE1-M5256-sds
VE1-M5256-elisa_1
VE1-R5257 Rhesus macaque Rhesus macaque VEGF R1 / Flt-1 Protein, Mouse IgG2a Fc Tag, low endotoxin
VE1-R5257-structure
VE1-R5257-sds
VE1-R5257-elisa_1

VEGF R1 Molecule Synonym Name

FLT,VEGFR1,FLT1

VEGF R1 Molecule Background

Vascular endothelial growth factor receptor 1 (VEGFR1) is also known as Fms-like tyrosine kinase 1 (FLT-1), Tyrosine-protein kinase receptor FLT, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR1 is detected in normal lung, but also in placenta, liver, kidney, heart and brain tissues and specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR1 acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR1 may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. VEGFR1 can promote endothelial cell proliferation, survival and angiogenesis in adulthood.

VEGF R1 References

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