There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > PDGF R alpha

PDGF R alpha

PDGF R alpha Molecule Information

Name:Platelet-derived growth factor receptor alpha
Target Synonym:RHEPDGFRA,Platelet-derived growth factor alpha receptor,PDGFRA,Alpha-type platelet-derived growth factor receptor,PDGFR-alpha,CD140a antigen,CD140a,Platelet Derived Growth Factor Receptor Alpha,Platelet-Derived Growth Factor Receptor, Alpha Polypeptide,Pl
Number of Launched Drugs:8
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Approved

PDGF R alpha Protein Product ListCompare or Buy

By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
PDA-H52H7 Human Human PDGF R alpha / PDGFRA Protein, His Tag

PDGF R alpha Molecule Synonym Name


PDGF R alpha Molecule Background

PDGFRA(platelet-derived growth factor receptor A), also termed PDGFR?(platelet-derived growth factor receptor ?), is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and thereby becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. The receptor is critical for the development of certain tissues and organs during embryogenesis and for the maintenance of these tissues and organs, particularly hematologic tissues, throughout life. Mutations in the gene which codes for PDGFRA, are associated with an array of clinically significant neoplasms.

PDGF R alpha References

PDGF R alpha Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Olaratumab IMC-3G3; LY-3012207 Approved Eli Lilly And Company Lartruvo United States Sarcoma s:20:"Eli Lilly And Co Ltd"; 2016-10-19 Solid tumours; Sarcoma; Prostatic Neoplasms; Gastrointestinal Stromal Tumors; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Pazopanib Hydrochloride GW-786034; SB-786034; GSK-786034; GW-786034B Approved Glaxosmithkline Plc, Novartis Pharma Ag 维全特, Armala, Patorma, Votrient Mainland China Carcinoma, Renal Cell s:26:"Novartis Pharma Schweiz Ag"; 2009-10-19 Osteosarcoma; Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Glioma; Uterine Cervical Diseases; Colorectal Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Ovarian Neoplasms; Breast Neoplasms; Sarcoma; Small Cell Lung Carcinoma; Carcinoma, Ovarian Epithelial; Hemangiosarcoma; Carcinoma, Renal Cell; Solid tumours; Uterine Diseases; Chondrosarcoma; Telangiectasia, Hereditary Hemorrhagic Details
Nintedanib Esylate BIBF-1120 Approved C.H. Boehringer Sohn Ag & Co. Kg Ofev, Vargatef Mainland China Idiopathic Pulmonary Fibrosis s:39:"Boehringer Ingelheim International Gmbh"; 2014-10-15 Ovarian Neoplasms; Solid tumours; Carcinoma, Renal Cell; Scleroderma, Systemic; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pulmonary Fibrosis; Multiple Myeloma; Prostatic Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Hepatic Insufficiency; Genital Neoplasms, Female; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
Regorafenib Monohydrate BAY-73-4506; DAST Approved Bayer Ag Stivarga, Resihance Mainland China Gastrointestinal Stromal Tumors s:15:"Bayer Pharma Ag"; 2012-09-27 Solid tumours; Rectal Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms Details
Sunitinib Malate SU-11248; SU-010398; PHA-290940; PNU-290940; PHA-290940AD; PNU-290940AD; SU-011248-L-malate salt; GB-102 Approved Pfizer Pharmaceuticals Ltd (China) 索坦, Sutent Japan Pancreatic neuroendocrine tumors (pNET) s:10:"Pfizer Inc"; 2006-01-26 Prostatic Neoplasms; Retinal Vein Occlusion; Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Urogenital Neoplasms; Urologic Neoplasms; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Breast Neoplasms; Diabetic macular oedema; Kidney Neoplasms; Urologic Diseases; Neuroendocrine Tumors; Kidney Diseases; Pancreatic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Stomach Neoplasms; Carcinoma, Islet Cell; Carcinoma, Renal Cell; Solid tumours; Liver Neoplasms Details
Lenvatinib Mesylate ER-203492-00; E-7080 Approved Eisai Co Ltd Kisplyx, Lenvima, Lenvima/Kisplyx, 乐卫玛 Mainland China Carcinoma, Hepatocellular s:16:"Eisai Europe Ltd"; 2015-02-13 Kidney Diseases; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Endometrial Neoplasms; Lymphoma; Thyroid Neoplasms; Hepatic Insufficiency; Liver Diseases; Solid tumours; Thyroid Carcinoma, Anaplastic; Adenocarcinoma of Lung; Renal Insufficiency; Carcinoma, Renal Cell; Ovarian Neoplasms; Biliary Tract Neoplasms; Liver Neoplasms Details
Ripretinib DCC-2618 Approved Deciphera Qinlock Canada Gastrointestinal Stromal Tumors s:29:"Deciphera Pharmaceuticals Llc"; 2020-05-15 Mastocytosis, Systemic; Gastrointestinal Stromal Tumors Details
Avapritinib BLU-285; CS-3007 Approved Blueprint Medicines Corporation Ayvakyt, Ayvakit EU Gastrointestinal Stromal Tumors s:36:"Blueprint Medicines (Netherlands) Bv"; 2020-01-09 Hematologic Neoplasms; Solid tumours; Mastocytosis, Systemic; Leukemia, Mast-Cell; Central Nervous System Neoplasms; Gastrointestinal Stromal Tumors Details

PDGF R alpha Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Anti-CMV monoclonal antibody (Humabs BioMed/Institute for Research in Biomedicine) Phase 2 Clinical Humabs Biomed, Institute For Research In Biomedicine Cytomegalovirus Infections Details
Chiauranib CS-2164 Phase 2 Clinical Shenzhen Chipscreen Biosciences Co Ltd Ovarian Neoplasms; Solid tumours; Small Cell Lung Carcinoma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular Details
Crenolanib Besylate ARO-002; CP-868596; ARO-002-26; IND-112201; CP-868596-26 Phase 3 Clinical Pfizer Pharmaceuticals Ltd (China) Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Gastrointestinal Stromal Tumors; Leukemia, Myeloid, Acute; Glioma; Carcinoma, Non-Small-Cell Lung Details
Lucitanib AL-3810; CO-3810; S-80881 Phase 3 Clinical Advenchen Laboratories Nanjing Ltd Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Transitional Cell; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Breast Neoplasms; Nasopharyngeal Carcinoma; Thymus Neoplasms; Genital Neoplasms, Female; Colorectal Neoplasms; Carcinoma, Small Cell; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details

This web search service is supported by Google Inc.