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CD8 alpha

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Cat. No. Species Product Description Structure Purity Feature
CDA-H52H3 Human Human CD8 alpha / CD8A Protein, His Tag
CDA-H52H3-structure
CDA-H52H3-sds
CDA-H52H3-elisa_1
CDA-H82E3 Human Biotinylated Human CD8 alpha / CD8A Protein, His,Avitag™
CDA-H82E3-structure
CDA-H82E3-sds
CDA-H82E3-elisa_1
CDA-M82E8 Mouse Biotinylated Mouse CD8 alpha / CD8A Protein, His,Avitag™
CDA-M82E8-structure
CDA-M82E8-sds

CD8 alpha Part of Bioactivity data

CDA-H82E3-ELISA
Biotinylated Human CD8 alpha, His,AvitagBiotinylated Human CD8 alpha, His,Avitag (Cat. No. CDA-H82E3) ELISA bioactivity

Immobilized Biotinylated Human CD8 alpha, His,Avitag (Cat. No. CDA-H82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate. can bind Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) with a linear range of 0.2-2 ng/mL (QC tested).

CDA-H52H3-ELISA
Human CD8 alpha, His TagHuman CD8 alpha, His Tag (Cat. No. CDA-H52H3) ELISA bioactivity

Immobilized Human CD8 alpha, His Tag (Cat. No. CDA-H52H3) at 1 μg/mL (100 μL/well) can bind Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) with a linear range of 0.2-39 ng/mL (QC tested).

CD8 alpha Molecule Synonym Name

CD8A,CD8,Leu2,MAL,p32

CD8 alpha Molecule Background

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

CD8 alpha References

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