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MIF

MIF Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
MIF-H82E7 Human Biotinylated Human MIF Protein, His Tag, Avi Tag (Avitag™)
MIF-H82E7-structure

MIF Molecule Synonym Name

MIF,GLIF,MMIF,GIF

MIF Molecule Background

Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL.  The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

MIF References

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