There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > MIF


MIF Molecule Information

Name:Macrophage migration inhibitory factor
Target Synonym:L-dopachrome tautomerase;Macrophage migration inhibitory factor;Glycosylation-inhibiting factor;L-dopachrome isomerase;GLIF ;GIF;MMIF;MIF;Phenylpyruvate tautomerase
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase ?

MIF Protein Product ListCompare or Buy

By Product Status:
By Product Category:
By Species:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
MIF-H82E7 Human Biotinylated Human MIF Protein, His,Avitag™

MIF Molecule Synonym Name


MIF Molecule Background

Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL.  The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

MIF References

MIF Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
CPSI-2705 CPS1-2705 Preclinical Cytokine PharmaSciences Infectious disease, Immunological disorders Details
Imalumab BAX-069; BAX-69 Phase Ⅱ Cytokine PharmaSciences, Baxalta Lupus nephritis, Solid tumours, Colorectal cancer, Malignant Ascites Details
R-ISO-15 Preclinical Ferring Pharmaceuticals Sepsis Details
CBX-21404 CBX-21404,CBX21404 Preclinical Ciblex Autoimmune diseases, Prostate cancer, Breast cancer, Inflammation Details

This web search service is supported by Google Inc.