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Your Position: Home > IgG2 Fc

IgG2 Fc

IgG2 Fc Protein Product ListCompare or Buy

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Cat. No.	Species	Product Description	Structure	Purity	Feature
IG2-H5206	Human	Human IgG2 Fc Protein, Tag Free (SPR verified)

IgG2 Fc Part of Bioactivity data

IG2-H5206-BLI

Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (Cat. No. FCN-H52W7) captured on CM5 Chip via anti-His antibody can bind Human IgG2 Fc, Tag Free (SPR verified) (Cat. No. IG2-H5206) with an affinity constant of 33.3 nM as determined in SPR assay (Biacore 8K) (QC tested).

Protocol

IgG2 Fc Molecule Synonym Name

IGHG2

IgG2 Fc Molecule Background

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-? (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).