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Your Position: Home > IgG2 Fc

IgG2 Fc

IgG2 Fc Part of Bioactivity data

IG2-H5206-ELISA

Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (Cat. No. FCN-H52W7) captured on CM5 Chip via anti-His antibody can bind Human IgG2 Fc, Tag Free (SPR verified) (Cat. No. IG2-H5206) with an affinity constant of 33.3 nM as determined in SPR assay (Biacore 8K) (QC tested).

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Cat. No.	Species	Product Description	Structure	Purity	Feature
IG2-H5206	Human	Human IgG2 Fc Protein, Tag Free (SPR verified)

IgG2 Fc Molecule Synonym Name

IGHG2

IgG2 Fc Molecule Background

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-? (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).