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IgG2 Fc

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Cat. No. Species Product Description Structure Purity Feature
IG2-H5206 Human Human IgG2 Fc Protein, Tag Free
IG2-H5206-structure
IG2-H5206-sds

IgG2 Fc Molecule Synonym Name

IGHG2

IgG2 Fc Molecule Background

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-? (IgG) antibody molecules changes in rheumatoid arthritis.  Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).

IgG2 Fc References

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