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Your Position: Home > B18R

B18R

B18R Protein Product ListCompare or Buy

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Cat. No.	Species	Product Description	Structure	Purity	Feature
B1R-H52H6	Vaccinia Virus	Vaccinia Virus B18R Protein, His Tag

B18R Part of Bioactivity data

B1R-H52H6-BLI

Vaccinia Virus B18R, His TagVaccinia Virus B18R, His Tag (Cat. No. B1R-H52H6) ELISA bioactivity

Immobilized Human IFN-α1a at 2 μg/mL (100 μL/well) can bind Vaccinia Virus B18R, His Tag (Cat. No. B1R-H52H6) with a linear range of 0.8-6 ng/mL (QC tested).

Protocol

B18R Molecule Synonym Name

B18R

B18R Molecule Background

B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.