CD163
CD163 Molecule Information
Name:Scavenger receptor cysteine-rich type 1 protein M130
Target Synonym:CD163;M130;Hemoglobin scavenger receptor
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Approved
CD163 Molecule Synonym Name
CD163,M130
CD163 Molecule Background
Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
CD163 References
CD163 Public Drug Information
| Name |
Research Code |
Research Phase |
Company |
First Brand Name |
First Approved Country |
First Indication |
First Approved Company |
First Approved Date |
Indications |
Clinical Trials |
| Tetrachlorodecaoxide |
OXO-K993; TCDO; WF-10 |
Approved |
NuvOx, Crescita Therapeutics |
|
|
|
|
|
Inflammation, Allergic rhinitis (AR), Immunological disorders |
Details
|
CD163 Clinical Drug Information
| Name |
Research Code |
Research Phase |
Company |
Indications |
Clinical Trials |
| TBI-304 |
HRC-304; TBI-304H; TBI-304 |
Phase Ⅰ |
Hemosol BioPharma |
Chemotherapy-induced anaemia |
Details
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