CD163 Protein - ACROBiosystems

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CD163

Brief Information

Name:Scavenger receptor cysteine-rich type 1 protein M130
Target Synonym:Scavenger receptor cysteine-rich type 1 protein M130,sCD163,CD163 Molecule,Hemoglobin Scavenger Receptor,CD163 Antigen,Macrophage-Associated Antigen,SCARI1,MM130,CD163,M130

Number of Launched Drugs:1
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved


CD3-H52E8	Human	Human CD163 Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

CD3-H52E8

Human

Human CD163 Protein, His Tag

Synonym Name

CD163,M130

Background

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

Clinical and Translational Updates

Public Drug Information

Name	Research Code	Research Phase	Company	First Brand Name	First Approved Country	First Indication	First Approved Company	First Approved Date	Indications	Clinical Trials
Tetrachlorodecaoxide	TCDO; WF-10; OXO-K993	Approved	NuvOx LLC	WF10, Oxoferin, Immunokine	Thailand	Rhinitis, Allergic; Inflammation	null	1997-01-01	HIV Infections; Rhinitis, Allergic; Inflammation	Details