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LRRC32

LRRC32 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
LR2-H5256 Human Human LRRC32 / GARP / Garpin Protein, Fc Tag
LR2-H5256-structure
LR2-H5256-sds
LR2-H5256-elisa_1

LRRC32 Molecule Synonym Name

GARP,Garpin,D11S833E

LRRC32 Molecule Background

Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naïve T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation.

LRRC32 References

LRRC32 Related Molecule

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