SIRP beta Protein Product ListCompare or Buy
SIRP beta Molecule Synonym Name
CD172b antigen, CD172b, DKFZp686A05192, FLJ26614, SIRP beta 1, SIRPB1, SIRP-BETA-1, 9930027N05Rik, SIRP-beta
SIRP beta Molecule Background
Signal-regulatory protein beta-1 (SIRP beta 1) also known as SIRP?1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. SIRP?1 is a transmembrane protein that has three Ig-like domains in its extracellular region and a short cytoplasmic tail. Human SIRP?1 is expressed on monocytes and granulocytes but not on lymphocytes. SIRP beta 1 contains short cytoplasmic domains that lack cytoplasmic sequence motifs capable of recruiting SHP-2 and SHP-1. In addition, they contain a single basic lysine residue within the hydrophobic transmembrane domain.
SIRP beta References
Gaikwad S., et al. 2009, Am J Pathol., 175(6), 2528-39.
Dietrich J., et al. 2000, J Immunol., 164(1), 9-12.
Tomasello E., et al. 2000, Eur J Immunol., 30(8), 2147-56.