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BTN3A2

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Cat. No. Species Product Description Structure Purity Feature
BT2-H82E7 Human Biotinylated Human BTN3A2 Protein, His,Avitag™
BT2-H82E7-structure
BT2-H82E7-sds

Synonym Name

BT3.2,BT3.3,BTF3,BTF4

Background

Butyrophilin subfamily 3 member A2(BTN3A2/BT3.2) mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC). We find that the three BTN3A isoforms: BTN3A1, BTN3A2, and BTN3A3, have high structural homology to the B7 superfamily of proteins and exist as V-shaped homodimers in solution, associating through the membrane proximal C-type Ig domain.

Clinical and Translational Updates

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