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Trastuzumab

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Cat. No. Species Product Description Structure Purity Feature
TRB-Y1b Mouse Anti-Trastuzumab Antibodies (recommended for PK/PD)
TRB-Y1b-sds
TRB-Y1b-elisa_1
TRB-Y5b Mouse Anti-Trastuzumab Antibodies (recommended for PK/PD)
TRB-Y5b-sds
TRB-Y5b-elisa_1

Part of Bioactivity data

TRB-Y5b-ELISA
Anti-Trastuzumab Antibodies (recommended for PK/PD)Anti-Trastuzumab Antibodies (recommended for PK/PD) (Cat. No. TRB-Y5b) ELISA bioactivity

Immobilized Trastuzumab at 1 μg/mL (100 μL/well) can bind Anti-Trastuzumab Antibodies (recommended for PK/PD) (Cat. No. TRB-Y5b) with a linear range of 0.19-6.25 ng/mL.

TRB-Y1b-ELISA
Anti-Trastuzumab AntibodiesAnti-Trastuzumab Antibodies (Cat. No. TRB-Y1b) ELISA bioactivity

Immobilized Trastuzumab at 1 μg/mL (100 μL/well) can bind Anti-Trastuzumab Antibodies (Cat. No. TRB-Y1b) with a linear range of 0.4-6 ng/mL (QC tested)

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Background

Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.

Clinical and Translational Updates

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