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Your Position: Home > IL-17 RE

IL-17 RE

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Cat. No. Species Product Description Structure Purity Feature
ILE-H5256 Human Human IL-17 RE (155-454) Protein, Fc Tag
ILE-H5256-structure
ILE-H5256-sds
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Part of Bioactivity data

ILE-H5256-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human IL-17 RE (155-454), Fc Tag (Cat. No. ILE-H5256) on Protein A Biosensor, can bind Human IL-17C, His Tag (Cat. No. ILC-H52H7) with an affinity constant of 0.714 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
ILE-H5256-ELISA
Human IL-17 RE (155-454), Fc TagHuman IL-17 RE (155-454), Fc Tag (Cat. No. ILE-H5256) ELISA bioactivity

Immobilized Human IL-17C, His Tag (Cat. No. ILC-H52H7) at 2 μg/mL (100 μL/well) can bind Human IL-17 RE (155-454), Fc Tag (Cat. No. ILE-H5256) with a linear range of 1-10 ng/mL (QC tested).

Protocol

Synonym Name

IL-17 RE,IL17RE,IL-17RE,IL-17 receptor E

Background

Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E. IL-17RE is known to be expressed in the pancreas, brain, and prostate. IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection.  IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells. Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.

Clinical and Translational Updates

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