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Your Position: Home > CD94

CD94

Brief Information

Name:Natural killer cells antigen CD94
Target Synonym:KLRD1,Killer Cell Lectin Like Receptor D1,Killer Cell Lectin-Like Receptor Subfamily D, Member 1,CD94 Antigen,Killer Cell Lectin-Like Receptor Subfamily D Member 1,NK Cell Lectin-Like Receptor Subfamily D
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
CD4-H52H8 Human Human CD94 Protein, His Tag
CD4-H52H8-structure
CD4-H52H8-sds
CD4-H5253 Human Human CD94 Protein, Mouse IgG2a Fc Tag
CD4-H5253-structure
CD4-H5253-sds
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Synonym Name

CD94,KLRD1,KP43,NK cell receptor

Background

CD94(Natural killer cells antigen CD94) is also known as KLRD1, KP43, NK cell receptor, Killer cell lectin-like receptor subfamily D member 1. CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.  CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
DR-01 DR-01 Phase 2 Clinical Dren Bio Inc Leukemia; Alopecia Areata; Enteropathy-Associated T-Cell Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma; Lymphoma, T-Cell; Vitiligo; Leukemia, Large Granular Lymphocytic; Autoimmune Diseases of the Nervous System Details

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