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CD24

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Part of Bioactivity data

CD4-H5257-ELISA
Human CD24, Mouse IgG2a Fc TagHuman CD24, Mouse IgG2a Fc Tag (Cat. No. CD4-H5257) ELISA bioactivity

Immobilized Human CD24, Mouse IgG2a Fc Tag (Cat. No. CD4-H5257) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 20-313 ng/mL (QC tested).

CD4-H52H5-ELISA
Human CD24, His tag (Nanoparticle)Human CD24, His tag (Nanoparticle) (Cat. No. CD4-H52H5) ELISA bioactivity

Immobilized Human CD24, His tag (Nanoparticle) (Cat. No. CD4-H52H5) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 5-78 ng/mL (QC tested).

Synonym Name

CD24,CD24A

Background

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Clinical and Translational Updates

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