Lipopolysaccharide-binding protein / LBP
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Lipopolysaccharide-binding protein / LBP Molecule Synonym Name
Lipopolysaccharide-binding protein,LBP
Lipopolysaccharide-binding protein / LBP Molecule Background
Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Lipopolysaccharide-binding protein / LBP References