CD206
CD206 Molecule Information
Name:Macrophage mannose receptor 1
Target Synonym:Macrophage mannose receptor 1-like protein 1?hMR?Macrophage mannose receptor 1?C-type lectin domain family 13 member D-like?CLEC13DL?MRC1L1?MRC1?Mannose Receptor C-Type 1?Mannose Receptor? C Type 1-Like 1?Human Mannose Receptor?MMR?Mannose Receptor? C Typ
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued
CD206 Molecule Synonym Name
MMR,CD206,hMR,MRC1,CLEC13D,CLEC13DL,MRC1L1
CD206 Molecule Background
CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.
CD206 References