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CD206

Brief Information

Name:Macrophage mannose receptor 1
Target Synonym:Macrophage mannose receptor 1-like protein 1,hMR,Macrophage mannose receptor 1,C-type lectin domain family 13 member D-like,CLEC13DL,MRC1L1,MRC1,Mannose Receptor C-Type 1,Mannose Receptor, C Type 1-Like 1,Human Mannose Receptor,MMR,Mannose Receptor, C Typ
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
CD6-H52H9 Human Human CD206 / MMR Protein, His Tag
CD6-H52H9-structure
CD6-H52H9-sds

Synonym Name

MMR,CD206,hMR,MRC1,CLEC13D,CLEC13DL,MRC1L1

Background

CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.

Clinical and Translational Updates

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