CD206 Protein - ACROBiosystems

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CD206

Brief Information

Name:Macrophage mannose receptor 1
Target Synonym:C-type lectin domain family 13 member D,Macrophage mannose receptor 1-like protein 1,hMR,Macrophage mannose receptor 1,C-type lectin domain family 13 member D-like,CLEC13DL,MRC1L1,MRC1,Mannose Receptor C-Type 1,Mannose Receptor, C Type 1-Like 1,Human Mannose Receptor,MMR,Mannose Receptor, C Type 1,CD206 Antigen,BA541I19.1,CD206,CLEC13D,Macrophage Mannose Receptor

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved


CD6-H52H9	Human	Human CD206 / MMR Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

CD6-H52H9

Human

Human CD206 / MMR Protein, His Tag

Synonym Name

MMR,CD206,hMR,MRC1,CLEC13D,CLEC13DL,MRC1L1

Background

CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.

Clinical and Translational Updates

Public Drug Information

Name	Research Code	Research Phase	Company	First Brand Name	First Approved Country	First Indication	First Approved Company	First Approved Date	Indications	Clinical Trials
Technetium Tc 99m tilmanocept	NEO3-09	Approved	University Of California	Lymphoseek Kit, Lymphoseek, Lymphoaim	India	Breast Neoplasms; Melanoma; Squamous Cell Carcinoma of Head and Neck; Diagnostic agents	Navidea Biopharmaceuticals Inc	2013-03-13	Head and Neck Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Breast Neoplasms; Diagnostic agents; Carcinoma, Squamous Cell; Melanoma	Details