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Your Position: Home > CD206

CD206

Brief Information

Name:Macrophage mannose receptor 1
Target Synonym:C-type lectin domain family 13 member D,Macrophage mannose receptor 1-like protein 1,hMR,Macrophage mannose receptor 1,C-type lectin domain family 13 member D-like,CLEC13DL,MRC1L1,MRC1,Mannose Receptor C-Type 1,Mannose Receptor, C Type 1-Like 1,Human Mannose Receptor,MMR,Mannose Receptor, C Type 1,CD206 Antigen,BA541I19.1,CD206,CLEC13D,Macrophage Mannose Receptor
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved

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By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
CD6-H52H9 Human Human CD206 / MMR Protein, His Tag
CD6-H52H9-structure
CD6-H52H9-sds

Synonym Name

MMR,CD206,hMR,MRC1,CLEC13D,CLEC13DL,MRC1L1

Background

CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Technetium Tc 99m tilmanocept NEO3-09 Approved University Of California Lymphoseek Kit, Lymphoseek, Lymphoaim India Breast Neoplasms; Melanoma; Squamous Cell Carcinoma of Head and Neck; Diagnostic agents Navidea Biopharmaceuticals Inc 2013-03-13 Head and Neck Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Breast Neoplasms; Diagnostic agents; Carcinoma, Squamous Cell; Melanoma Details

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