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PADI2

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Part of Bioactivity data

PA2-C5545-MALS-HPLC
Cynomolgus PADI2, His Tag (Cat. No. ) MALS images

The purity of Cynomolgus PADI2, His Tag (Cat. No. PA2-C5545) was more than 85% and the molecular weight of this protein is around 136-167 kDa verified by SEC-MALS.

  • Background
    Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
  • Clinical and Translational Updates
      
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    PA2-M5544-MALS-HPLC
    Mouse PADI2, His Tag (Cat. No. ) MALS images

    The purity of Mouse PADI2, His Tag (Cat. No. PA2-M5544) was more than 85% and the molecular weight of this protein is around 140-171 kDa verified by SEC-MALS.

Synonym Name

PADI2,PAD-H19,KIAA0994,PAD2,PDI2

Background

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer.  This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

Clinical and Translational Updates

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