IFN-alpha 1 Protein - ACROBiosystems

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IFN-alpha 1


IFA-H5258	Human	Human IFN-alpha 1 Protein, Fc Tag
IFA-H52H9	Human	Human IFN-alpha 1 Protein, His Tag
IFA-M52H3	Mouse	Mouse IFN-alpha 1 Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

IFA-H5258

Human

Human IFN-alpha 1 Protein, Fc Tag

IFA-H52H9

Human

Human IFN-alpha 1 Protein, His Tag

IFA-M52H3

Mouse

Mouse IFN-alpha 1 Protein, His Tag

Part of Bioactivity data

IFA-H52H9-BLI

Loaded Human IFN-alpha 1, His Tag (Cat. No. IFA-H52H9) on HIS1K Biosensor, can bind Human IFNAR1, Fc Tag (Cat. No. IF1-H5253) with an affinity constant of 0.191 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

IFA-H52H9-BLI

Loaded Human IFN-alpha 1, His Tag (Cat. No. IFA-H52H9) on HIS1K Biosensor, can bind Human IFNAR2, Fc Tag (Cat. No. IF2-H5255) with an affinity constant of 19.5 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

IFN-alpha 1,IFNA1,IFNalpha 1,IFN-alpha-1,LeIF D

Background

Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.

Clinical and Translational Updates