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Your Position: Home > IFN-alpha 1

IFN-alpha 1

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Cat. No. Species Product Description Structure Purity Feature
IFA-H5258 Human Human IFN-alpha 1 Protein, Fc Tag (MALS verified)
IFA-H5258-structure
IFA-H5258-sds
IFA-H52H9 Human Human IFN-alpha 1 Protein, His Tag
IFA-H52H9-structure
IFA-H52H9-sds
IFA-M52H3 Mouse Mouse IFN-alpha 1 Protein, His Tag
IFA-M52H3-structure
IFA-M52H3-sds

Part of Bioactivity data

IFA-H5258-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human IFN-alpha / beta R1, His Tag (Cat. No. IF1-H5225) on NTA Biosensor, can bind Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) with an affinity constant of 11.3 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

Protocol
IFA-H5258-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human IFNAR2, His Tag (Cat. No. IF2-H5224) on HIS1K Biosensor, can bind Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) with an affinity constant of 2.67 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

IFN-alpha 1,IFNA1,IFNalpha 1,IFN-alpha-1,LeIF D

Background

Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.

Clinical and Translational Updates

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