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Gastrin-17

Brief Information

Name:Gastrin 17
Target Synonym:Gastrin component II,Gastrin component III,GAS,G52,G34,G14,G17,G6,GAST,Gastrin component I,Gastrin-34,Gastrin-17,Gastrin,Preprogastrin
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 3 Clinical

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Cat. No. Species Product Description Structure Purity Feature
GA7-H82F4 Human Biotinylated Human Gastrin-17 Protein, Fc,Avitag™ (MALS verified)
GA7-H82F4-sds
GA7-H82F4-elisa_1

Part of Bioactivity data

GA7-H82F4-MALS-HPLC
Biotinylated Human Gastrin-17, Fc,Avitag (Cat. No. ) MALS images

The purity of Biotinylated Human Gastrin-17, Fc,Avitag (Cat. No. GA7-H82F4) was more than 90% and the molecular weight of this protein is around 60-70 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Human Gastrin-17, Fc,AvitagBiotinylated Human Gastrin-17, Fc,Avitag (Cat. No. GA7-H82F4) ELISA bioactivity

Immobilized Anti-Gastrin-17 antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Biotinylated Human Gastrin-17, Fc,Avitag (Cat. No. GA7-H82F4) with a linear range of 0.1-2.5 ng/mL (QC tested).

GA7-H82F4-ELISA
Biotinylated Human Gastrin-17, Fc,AvitagBiotinylated Human Gastrin-17, Fc,Avitag (Cat. No. GA7-H82F4) ELISA bioactivity

Immobilized Anti-Gastrin-17 antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Biotinylated Human Gastrin-17, Fc,Avitag (Cat. No. GA7-H82F4) with a linear range of 0.1-2.5 ng/mL (QC tested).

Synonym Name

gastrin-17,gastrin 17,gastrin

Background

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Polyclonal antibody stimulator (Cancer Advances) G-17DT Phase 3 Clinical Aphton Corp Stomach Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Colorectal Neoplasms; Jaundice Details

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