Login Register
icon_bulk_orderBulk order Acrobiosystems for ChineseChinese
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
SARS-CoV-2  Delta Mu C.1.2| Claudin 18.2 | CD20 | CD3 | GPCRs | IL-2R
0
There is no goods in the shopping cart !
My Cart
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Integrin isoform alpha-7X1B beta 1

Integrin isoform alpha-7X1B beta 1

Product ListCompare or Buy

Product> Filter Results
By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
IT1-C52W3 Cynomolgus Cynomolgus Integrin isoform alpha-7X1B beta 1 (ITGA7X1B&ITGB1) Heterodimer Protein, Tag Free&His Tag (MALS verified)
IT1-C52W3-structure
IT1-C52W3-sds

Part of Bioactivity data

IT1-C52W3-ELISA
Cynomolgus ITGA7X1B&ITGB1 Heterodimer Protein, Tag Free&His Tag (Cat. No. ) MALS images

The purity of Cynomolgus ITGA7X1B&ITGB1 Heterodimer Protein, Tag Free&His Tag (Cat. No. IT1-C52W3) was more than 90% and the molecular weight of this protein is around 208-254 kDa verified by SEC-MALS.

Report
  • Background
    Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

integrin alpha-7 isoform X1B beta 1,ITGA7X1B&ITGB1,ITGA7X1BB1

Background

Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3.

Clinical and Translational Updates

This web search service is supported by Google Inc.

totop
Call us
Call us
North America: +1 800-810-0816 (Toll Free)
Asia & Pacific: +86 400-682-2521
Email
Email
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
1 Innovation Way, Newark, DE 19711, USA
linkedin twitter facebook

Leave a message

Copyright © 2017 ACROBiosystems. All Rights Reserved
中文网站|Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap