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Your Position: Home > FGF-7

FGF-7

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Cat. No. Species Product Description Structure Purity Feature
FG7-H51H5 Human Human FGF-7 / HBGF-7 / KGF Protein, His Tag
FG7-H51H5-structure
FG7-H82E7 Human Biotinylated Human FGF-7 / HBGF-7 / KGF Protein, His,Avitag™ (MALS verified)
FG7-H82E7-structure
FG7-H82E7-sds

Part of Bioactivity data

FG7-H82E7-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Human FGF-7, His,Avitag (Cat. No. FG7-H82E7) on SA Biosensor, can bind Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) with an affinity constant of 37 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

Protocol
FG7-H82E7-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Human FGF-7, His,Avitag (Cat. No. FG7-H82E7) on SA Biosensor, can bind Human FGF R1, His Tag (Cat. No. FG1-H5223) with an affinity constant of 243 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

FGF-7,Fibroblast growth factor 7,HBGF-7,Keratinocyte growth factor,KGF

Background

Fibroblast growth factor (FGF) 7 (is also known as Keratinocyte growth factor (KGF)), a member of FGF family, is initially found to be secreted from mesenchymal cells to repair epithelial tissues. As a well-characterized paracrine growth factor for tissue growth and regeneration, fibroblast growth factor 7 (FGF7) is involved in a number of physiological and pathological processes, including lung disease and cancer. The stromal-derived FGFs, such as FGF7 and FGF10, control epithelial cell resident FGFR2IIIb activities, promote net tissue homeostasis, and restraint tumor cells from progression to malignancy.

Clinical and Translational Updates

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