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Your Position: Home > Gastrin-71

Gastrin-71

Brief Information

Name:Gastrins
Target Synonym:Gastrins
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Cat. No. Species Product Description Structure Purity Feature
GAN-M5253 Mouse Mouse Gastrin-71 Protein, Fc tag
GAN-M5253-structure
GAN-M5253-sds
GAN-H5253 Human Human Gastrin-71 Protein, Fc tag
GAN-H5253-structure
GAN-H5253-sds
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Synonym Name

Gastrin-71,Gastrin,GAST,Gastrin component

Background

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.

Clinical and Translational Updates

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